CAS 15180-00-4

Prednival

Description:

Prednival, with the CAS number 15180-00-4, is a synthetic corticosteroid that exhibits anti-inflammatory and immunosuppressive properties. It is primarily used in the treatment of various inflammatory and autoimmune conditions, such as allergies, asthma, and certain skin disorders. The compound functions by mimicking the effects of cortisol, a natural hormone produced by the adrenal glands, thereby modulating the immune response and reducing inflammation. Prednival is typically administered in oral form, and its pharmacological effects include the inhibition of leukocyte infiltration at the site of inflammation, suppression of humoral immune responses, and the reduction of edema and pain. Like other corticosteroids, it may have side effects, including potential impacts on metabolism, immune function, and the endocrine system, necessitating careful monitoring during treatment. Its use should be guided by a healthcare professional to balance therapeutic benefits against possible adverse effects.

Formula: C₂₆H₃₆O₆

InChI: InChI=1S/C26H36O6/c1-4-5-6-22(31)32-26(21(30)15-27)12-10-19-18-8-7-16-13-17(28)9-11-24(16,2)23(18)20(29)14-25(19,26)3/h9,11,13,18-20,23,27,29H,4-8,10,12,14-15H2,1-3H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1

InChI key: InChIKey=BOFKYYWJAOZDPB-FZNHGJLXSA-N

SMILES: O(C(CCCC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]

Synonyms:

• (11Beta)-11,21-Dihydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Pentanoate
• (11β)-11,21-Dihydroxy-17-[(1-oxopentyl)oxy]pregna-1,4-diene-3,20-dione
• 11,21-Dihydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Pentanoate
• Prednisolone 17-valerate
• Prednival
• Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-17-[(1-oxopentyl)oxy]-, (11β)-
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-, 17-valerate
• W 4869

Prednival

Controlled Product

CAS: 15180-00-4

Applications Prednival was used in the study of inflammation-inhibiting activity of steroids.
References Bodor, N., et al.: J. Med. Chem., 26, 318 (1983); Stouch, T., et al.: J. Med. Chem., 29, 2125 (2986);

Formula: C₂₆H₃₆O₆

Color and Shape: Neat

Molecular weight: 444.56

Ref: TR-P703918

Prednival

CAS: 15180-00-4

Prednival is a biochemical.

Formula: C₂₆H₃₆O₆

Color and Shape: Solid

Molecular weight: 444.56

Ref: TM-T34127

[(8S,9R,10R,11S,13S,14S,17R)-11-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[A

Controlled Product

CAS: 15180-00-4

Hydrocortisone is a synthetic glucocorticoid that is used as an immunoregulatory and anti-inflammatory agent. It binds to the glucocorticoid receptor, which is found in many cells in the body, including those involved in inflammatory skin diseases. Hydrocortisone has been shown to be effective against lichenified skin conditions. It has a constant binding affinity for the glucocorticoid receptor and can be activated by removal of the 17-valerate group. Hydrocortisone is also known as betamethasone, which is an analog of hydrocortisone that has a hydroxyl group instead of a methyl group on carbon 18. Betamethasone does not bind to the glucocorticoid receptor and therefore does not exhibit any anti-inflammatory properties.

Formula: C₂₆H₃₆O₆

Purity: Min. 95%

Molecular weight: 444.6 g/mol

Ref: 3D-QAA18000

Prednisolone-17-Valerate

CAS: 15180-00-4

Formula: C₂₆H₃₆O₆

Molecular weight: 444.57

Ref: ST-EA-CP-P20040