CAS 15183-37-6: Estetrol
Description:Estetrol is a synthetic estrogen that is primarily used in hormonal therapies, particularly in contraceptives and hormone replacement therapies. It is characterized by its unique structure, which includes a hydroxyl group that contributes to its estrogenic activity. Estetrol is notable for its relatively mild estrogenic effects compared to other synthetic estrogens, making it a subject of interest for developing therapies with fewer side effects. Its pharmacokinetic profile indicates that it has a favorable absorption and metabolism, leading to a lower risk of thromboembolic events compared to traditional estrogens. Additionally, Estetrol exhibits a selective action on estrogen receptors, which may provide therapeutic benefits while minimizing adverse effects. The substance is typically administered orally and is recognized for its potential in improving women's health, particularly in managing menopausal symptoms and providing contraceptive options. As research continues, Estetrol's safety and efficacy profile is being evaluated to better understand its role in modern medicine.
Formula:C18H24O4
InChI:InChI=1S/C18H24O4/c1-18-7-6-12-11-5-3-10(19)8-9(11)2-4-13(12)14(18)15(20)16(21)17(18)22/h3,5,8,12-17,19-22H,2,4,6-7H2,1H3/t12-,13-,14-,15-,16-,17+,18+/m1/s1
InChI key:InChIKey=AJIPIJNNOJSSQC-NYLIRDPKSA-N
SMILES:OC1=CC=C2C(=C1)CCC3C2CCC4(C)C(O)C(O)C(O)C34
- Synonyms:
- (15Alpha,16Alpha,17Beta)-Estra-1,3,5(10)-Triene-3,15,16,17-Tetrol
- (15a,16a,17)-Estra-1,3,5(10)-triene-3,15,16,17-tetrol
- (15α,16α,17β)-Estra-1,3,5(10)-triene-3,15,16,17-tetrol
- 1,3,5(10)-Estratrien-3,15-Alpha, 16-Alpha, 17-Beta-Tetrol
- 15-Alpha-Hydroxyestriol
- 15a-Hydroxyestriol
- 3,15a,16a,17-Tetrahydroxyestra-1,3,5(10)-triene
- 3,15α,16α,17β-Tetrahydroxyestra-1,3,5(10)-triene
- E 4
- Enb 39R14Vf
- See more synonyms
- Estra-1,3,5(10)-trien-3,15α,16α,17β-tetraol
- Estra-1,3,5(10)-triene-3,15,16,17-tetrol, (15α,16α,17β)-
- Estra-1,3,5(10)-triene-3,15a,16a,17-tetrol
- Estra-1,3,5(10)-triene-3,15α,16α,17β-tetrol
- Estetrol