CAS 151988-33-9

AC2-26

Description:

AC2-26, with the CAS number 151988-33-9, is a synthetic compound that has garnered interest in various fields, particularly in medicinal chemistry. It is characterized by its unique molecular structure, which typically includes specific functional groups that contribute to its biological activity. AC2-26 is known for its role as a selective inhibitor, often targeting specific enzymes or receptors within biological systems, which can lead to therapeutic effects in certain diseases. The compound is usually studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME), which are crucial for understanding its efficacy and safety profile. Additionally, AC2-26 may exhibit varying degrees of solubility in different solvents, influencing its formulation and delivery methods in pharmaceutical applications. As with many chemical substances, its stability under various conditions, such as temperature and pH, is also an important characteristic that affects its usability in research and clinical settings. Overall, AC2-26 represents a significant area of study in the development of new therapeutic agents.

Formula: C₁₄₁H₂₁₀N₃₂O₄₄S

Annexin A1 (1-25) (dephosphorylated) (human)

CAS: 151988-33-9

Annexin A1 (AnxA1) N-terminal-derived peptide, also known as Ac2-26, mimics the antiinflammatory effects of AnxA1. Ac2-26 can activate all three formyl peptide receptor family members FPR, FPR-like (FPRL)1 and FPRL2 at similar concentations. It represents the first endogenous ligand for FPRL2. In myocardial ischemia-reperfusion injury experiments the peptide showed cardioprotective effects. Understanding the underlying mechanism may help developing novel therapeutics for acute cardioprotection.

Formula: C₁₄₁H₂₁₀N₃₂O₄₄S

Purity: 95.3%

Color and Shape: White

Molecular weight: 3089.47

Ref: 01-4026282

Ac2-26

CAS: 151988-33-9

Ac2-26, an annexin A1 mimetic peptide,inflammatory diabetic p38MAPK/NF-κB,sepsis-induced cardiomyocyte apoptosis LXA4/PI3K/AKT, IL-22/IL-22R1/STAT3.

Formula: C₁₄₁H₂₁₀N₃₂O₄₄S

Purity: 98.78%

Color and Shape: Solid

Molecular weight: 3089.43

Ref: TM-TP1373

Annexin A1(1-25)(dephosphorylated)(human)ammonium salt

CAS: 151988-33-9

Annexin A1 is a phospholipid-binding protein that is involved in the regulation of inflammation. It is often found in atherosclerotic lesions and has been shown to be an anti-inflammatory cytokine. Annexin A1 (dephosphorylated) does not inhibit the activity of enzymes such as cyclooxygenase and lipoxygenase, and so it may have therapeutic potential for treatment of autoimmune diseases such as Crohn's disease or bowel disease. Annexin A1 also has anti-inflammatory properties, which may be due to its ability to inhibit the production of proinflammatory cytokines such as IL-6 and TNF-α by inhibiting the activation of NFκB.

Formula: C₁₄₁H₂₁₀N₃₂O₄₄S·NH₄

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 3,107.47 g/mol

Ref: 3D-FA108920