CAS 152-11-4
:Verapamil hydrochloride
Description:
Verapamil hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension, angina pectoris, and certain types of arrhythmias. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. The compound works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to relaxation of the vascular smooth muscle and a decrease in heart rate. This mechanism helps to lower blood pressure and reduce the workload on the heart. Verapamil hydrochloride has a relatively low bioavailability due to extensive first-pass metabolism, and its pharmacokinetics can be influenced by factors such as age, liver function, and concurrent medications. Common side effects may include dizziness, headache, and gastrointestinal disturbances. As with any medication, it is essential to use verapamil hydrochloride under medical supervision to manage potential interactions and contraindications effectively.
Formula:C27H38N2O4·ClH
InChI:InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H
InChI key:InChIKey=DOQPXTMNIUCOSY-UHFFFAOYSA-N
SMILES:C(CCCN(CCC1=CC(OC)=C(OC)C=C1)C)(C(C)C)(C#N)C2=CC(OC)=C(OC)C=C2.Cl
Synonyms:- (+/-)-5-[N-(3,4-dimethoxyphenylethyl)-METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYLVALERONITRILE HYDROCHLORIDE
- 2-(3,4-Dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]-2-(propan-2-yl)pentanenitrile hydrochloride
- 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-Dimethoxyphenyl)Ethyl](Methyl)Amino}-2-(Propan-2-Yl)Pentanenitrile Hydrochloride (1:1)
- 5-[(3,4-DIMETHOXYPHENETHYL)METHYLAMINO]-2-(3,4-dimethoxyphenyl)-2-ISOPROPYL-VALERONITRILE HYDROCHLORIDE
- Akilen
- Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-
- Alpha-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)Propyl)-3,4-Dimethoxy-Alpha-(1-Methylethyl)-Benzeneacetonitrile Hydrochloride
- Anpec
- Apo-Verap
- Apoacor
- Arapamyl
- Azupamil
- Benzeneacetonitrile Hydrochloride
- Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, hydrochloride (1:1)
- Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, monohydrochloride
- Berkatens
- Calan
- Calan SR
- Calaptin
- Calaptin 240SR
- Calaptin 80
- Cardiabeltin
- Cardiagutt
- Cardibeltin
- Caveril
- Civicor
- Civicor Retard
- Coraver
- Cordilox
- Cordilox SR
- Corpamil
- Covera HS
- Dignover
- Dilacoran
- Dilacoran HTA
- Drosteakard
- Finoptin
- Flamon
- Geangin
- Hexasoptin
- Hexasoptin Retard
- Ikacor
- Ikapress
- Iproveratril
- Iproveratril hydrochloride
- Iproveratrilhydrochloride
- Iso-Card SR
- Isoptin
- Isoptin Retard
- Isoptin SR
- Isoptin, hydrochloride
- Isoptine
- Isoptino
- Izoptin hydrochloride
- Izoptinhydrochloride
- Lekoptin Retard
- Lu 20175
- Manidon
- Manidon Retard
- NSC 272366
- NSC 657799
- Novo-Veramil
- Quasar
- Ravamil SR
- Securon
- Univer
- Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, hydrochloride
- Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride
- Vasolan
- Vasomil
- Vasopten
- Veracaps SR
- Veracim
- Veracor
- Verahexal
- Veraloc
- Veramex
- Veramil
- Verapamil HCl
- Verapin
- Verapress 240SR
- Veraptin
- Verdilac
- Verelan
- Verelan SR
- Verexamil
- Verogalid ER
- Verpal
- Vetrimil
- dl-Verapamil hydrochloride
- (+/-)-Verapamil hydrochloride
- See more synonyms
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Found 24 products.
Verapamil Hydrochloride
CAS:Formula:C27H38N2O4·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:491.07(+/-)-Verapamil hydrochloride, 99+%
CAS:<p>A calcium channel blocker with a chemopreventive character</p>Formula:C27H39ClN2O4Purity:99+%Molecular weight:491.07Verapamil hydrochloride
CAS:Verapamil hydrochlorideFormula:C27H38N2O4HClPurity:99.7%Color and Shape:White To Off-WhiteMolecular weight:490.25984VERAPAMIL HYDROCHLORIDE RS
CAS:<p>VERAPAMIL HYDROCHLORIDE RS</p>Formula:C27H39ClN2O4Molecular weight:491.0626Verapamil Hydrochloride
CAS:<p>Nitrile function compounds, not elsewhere specified or included</p>Formula:C27H38N2O4·HClColor and Shape:White Off-White Solid Crystalline PowderMolecular weight:490.259842-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile hydrochloride
CAS:Formula:C27H39ClN2O4Purity:99%Color and Shape:SolidMolecular weight:491.0626Verapamil hydrochloride
CAS:<p>Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.</p>Formula:C27H39ClN2O4Purity:98.7% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:491.06Verapamil hydrochloride
CAS:Formula:C27H38N2O4·HClPurity:≥ 98.0%Color and Shape:White to almost white powderMolecular weight:491.07Verapamil hydrochloride
CAS:<p>Verapamil hydrochloride</p>Formula:C27H38N2O4·ClHPurity:99%Color and Shape: white powderMolecular weight:491.06g/mol(±)-Verapamil-d3 HCl(N-methyl-d3)
CAS:Purity:99 atom % DColor and Shape:White To Off-White SolidMolecular weight:494.09Verapamil Hydrochloride
CAS:Controlled Product<p>Applications A calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)<br></p>Formula:C27H38N2O4·ClHColor and Shape:NeatMolecular weight:491.06Verapamil hydrochloride
CAS:<p>L-type calcium channel blocker</p>Formula:C27H39ClN2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:491.06 g/molVerapamil HCl - Bio-X ™
CAS:<p>Verapamil is drug that belongs to the class of drugs known as calcium channel blockers. It is used to treat high blood pressure, angina and other cardiovascular disorders. It works by relaxing the blood vessels so that blood can flow more easily. It does this by inhibiting the calcium ion influx through slow channels into conductile, contractile myocardial cells and vascular smooth muscle cells.</p>Formula:C27H38N2O4•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:491.06 g/molVerapamil hydrochloride
CAS:Formula:C27H39ClN2O4Purity:98.0%Color and Shape:SolidMolecular weight:491.07
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