CAS 152-72-7: (±)-Acenocoumarol
Description:(±)-Acenocoumarol is a synthetic anticoagulant belonging to the coumarin class, primarily used in the prevention and treatment of thromboembolic disorders. It functions by inhibiting vitamin K epoxide reductase, which is crucial for the synthesis of vitamin K-dependent clotting factors in the liver. This action effectively reduces blood coagulation, making it valuable in clinical settings. The compound is a racemic mixture, meaning it contains equal parts of two enantiomers, which can exhibit different pharmacological properties. Acenocoumarol is typically administered orally and has a relatively rapid onset of action compared to other anticoagulants. Its pharmacokinetics can be influenced by various factors, including diet, genetic variations, and interactions with other medications, necessitating careful monitoring of coagulation parameters. Side effects may include bleeding complications, which require vigilant management. Overall, (±)-Acenocoumarol is an important therapeutic agent in anticoagulation therapy, with specific characteristics that necessitate individualized patient care.
Formula:C19H15NO6
InChI:InChI=1S/C19H15NO6/c1-11(21)10-15(12-6-8-13(9-7-12)20(24)25)17-18(22)14-4-2-3-5-16(14)26-19(17)23/h2-9,15,22H,10H2,1H3
InChI key:InChIKey=VABCILAOYCMVPS-UHFFFAOYSA-N
SMILES:O=C1OC=2C=CC=CC2C(O)=C1C(C3=CC=C(C=C3)N(=O)=O)CC(=O)C
- Synonyms:
- (.+-.)-Acenocoumarin
- (.+-.)-p-Nitrowarfarin
- 2-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-4H-chromen-4-one
- 2H-1-Benzopyran-2-one, 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-
- 3-(Alpha-acetonyl-4-nitrobenzyl)-4-hydroxycoumarin
- 3-(α-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin
- 3-(α-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin
- 3-(α-p-Nitrophenyl-β-acetylethyl)-4-hydroxycoumarin
- 3-[2-Acetyl-1-(p-nitrophenyl)ethyl]-4-hydroxycoumarin
- 3-[α-(4'-Nitrophenyl)-β-acetylethyl]-4-hydroxycoumarin
- See more synonyms
- 3-[α-(p-Nitrophenol)-β-acetylethyl]-4-hydroxycoumarin
- 4-Hydroxy-2-oxo-3-[3-oxo-1-(4-nitrophenyl)butyl]-2H-chromene
- 4-Hydroxy-3-(1-(4-Nitrophenyl)-3-Oxobutyl)Coumarin
- 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one
- 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one
- <span class="text-smallcaps">DL</span>-3-(α-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin
- Acebron
- Acenokumarol
- Acitrom
- Ascumar
- Coumarin, 3-(α-acetonyl-p-nitrobenzyl)-4-hydroxy-
- DL-3-(α-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin
- G 23,350
- Minisintrom
- Neo-Sintrom
- Nicoumalone
- Nitrowarfarin
- Sincoumar
- Sinkumar
- Sinthrom
- Sinthrome
- Sintrom
- Sintrom Mitis
- Sintroma
- Syncoumar
- Syncumar
- Syntrom
- Trombostop
- Zotil
- disodium 5'-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]adenosine
- Acenocoumarol
