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CAS 1520010-86-9

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Sofosbuvir IMpurity

Description:
Sofosbuvir impurity, identified by its CAS number 1520010-86-9, is a chemical compound associated with the antiviral drug Sofosbuvir, which is primarily used in the treatment of hepatitis C. As an impurity, it may arise during the synthesis or degradation of Sofosbuvir and is typically characterized by its molecular structure, which may include specific functional groups that influence its chemical behavior. Impurities like this can affect the efficacy and safety of pharmaceutical formulations, making their identification and quantification crucial in drug development and quality control processes. The characteristics of such impurities often include their solubility in various solvents, stability under different conditions, and potential biological activity. Regulatory agencies require thorough analysis of impurities to ensure that they do not exceed acceptable limits in pharmaceutical products. Understanding the properties of Sofosbuvir impurity is essential for ensuring the overall quality and safety of the final drug product.
Formula:C12H18NO5P
Synonyms:
  • Sofosbuvir Phosphate Impurity
  • Sofosbuvir Phenoxyphosphinyl Impurity
  • Sofosbuvir IMpurity
  • L-Alanine, N-(hydroxyphenoxyphosphinyl)-, 1-methylethyl ester
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Found 2 products.
  • Sofosbuvir Impurity 43 Cyclohexylamine Salt
    TLC
    + Info

    Sofosbuvir Impurity 43 Cyclohexylamine Salt

    CAS:
    Formula:C12H18NO5P·C6H13N
    Color and Shape:White To Off-White Solid
    Molecular weight:287.25 99.18

    Ref: 4Z-S-055049

    5mg
    To inquire
    10mg
    508.00€
    25mg
    825.00€
    50mg
    1,153.00€
    100mg
    To inquire
  • Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt
    TRC
    + Info

    Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt

    Controlled Product
    CAS:
    <p>Applications Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt is an impurity of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.<br>References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010);<br></p>
    Formula:C12H17NNaO5P
    Color and Shape:Neat
    Molecular weight:309.23

    Ref: TR-I824640

    10g
    1,509.00€