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CAS 152089-12-8

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DOCETAXEL SIDE CHAIN NO 1

Description:
Docetaxel Side Chain No. 1, with the CAS number 152089-12-8, is a chemical compound that serves as a key intermediate in the synthesis of the anticancer drug docetaxel, which is used primarily in the treatment of various cancers, including breast and lung cancer. This compound features a complex structure characterized by a taxane core, which is essential for its biological activity. The side chain contributes to the compound's solubility and pharmacokinetic properties, influencing its efficacy and stability. Docetaxel and its derivatives function by inhibiting microtubule depolymerization, thereby disrupting normal cell division and leading to apoptosis in rapidly dividing cancer cells. The compound is typically synthesized through multi-step organic reactions, and its purity and structural integrity are critical for ensuring the desired therapeutic effects. As with many pharmaceutical intermediates, handling and storage require adherence to safety protocols to mitigate risks associated with chemical exposure.
Formula:C18H25NO5
Synonyms:
  • (3r,4s)-1-Tert-Butoxycarbonyl-3-(2-Ethoxyethoxy)-4-Phenyl-2-Azetidione
  • (3R,4S)-1-Tert-Butylcarbonyl-3-(2-Ethoxyethoxyl)-4-Phenyl-2-Azetidinone
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