CAS 152460-10-1

6-Methyl-N-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine

Description:

6-Methyl-N-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine, with the CAS number 152460-10-1, is a chemical compound characterized by its complex structure, which includes a benzene ring substituted with amino groups and a methyl group, as well as a pyrimidine and pyridine moiety. This compound typically exhibits properties associated with aromatic amines, such as potential solubility in organic solvents and moderate polarity. The presence of nitrogen-containing heterocycles like pyridine and pyrimidine may impart unique electronic properties, influencing its reactivity and potential biological activity. It may also participate in hydrogen bonding due to the amino groups, which can affect its interactions in various chemical environments. Additionally, compounds of this nature are often investigated for their potential applications in pharmaceuticals, agrochemicals, or as intermediates in organic synthesis. However, specific physical properties such as melting point, boiling point, and solubility would need to be determined experimentally or sourced from reliable databases for precise applications.

Formula: C₁₆H₁₅N₅

InChI: InChI=1S/C16H15N5/c1-11-4-5-13(17)9-15(11)21-16-19-8-6-14(20-16)12-3-2-7-18-10-12/h2-10H,17H2,1H3,(H,19,20,21)

InChI key: InChIKey=QGAIPGVQJVGBIA-UHFFFAOYSA-N

SMILES: N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=C(C)C=CC(N)=C3

Synonyms:

• 1,3-Benzenediamine 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-
• 1,3-Benzenediamine, 4-methyl-N³-[4-(3-pyridinyl)-2-pyrimidinyl]-
• 2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine
• 4-Methyl-3-[4-(3-pyridinyl)pyrimidin-2-ylamino]aniline
• 4-Methyl-N'-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine
• 4-Methyl-N3-[4-(3-pyridinyl)-2-pyrimidin-yl]-1,3-benzenediamine
• 4-Methyl-N³-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine
• 4-Methyl-N³-[4-(pyridin-3-yl)pyrimidin-2-yl]-1,3-benzenediamine
• 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine
• 4-methyl-N~3~-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine
• 6-methyl-N'-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine
• N-(2-Methyl-5-Amino Phenyl)-4-(3-Pyridyl)-2-Pyrimidine
• N-(2-Methyl-5-aminophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
• N-(2-methyl-5-aminophenyl)-4-(3-pyridyl)-2-pyrimidine amine
• N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
• N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine
• N-(5-Amino-2-methylphenyl)-4-(pyridin-3-yl)pyrimidin-2-ylamine
• N-(5-Amino-2-methylphenyl)-6-(pyridin-3-yl)-2-pyrimidinamine
• N-(5-Amino-2-methylphenyl)-N-[4-(3-pyridyl)pyrimidin-2-yl]amine
• N-(5-Amino-2-methylphenyl)[4-(3-pyridyl)-2-pyrimidinyl]amine
• N-(5-amino-2-methylphenl)-4-(3-pyridyl)-2-pyrimidine-amine
• N-(5-amino-2-methylphenyl)-4-(3-pyrdyl)-2-pydimidineamine
• N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine

2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Purity: >98.0%(T)(HPLC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 277.33

Ref: 3B-A2308

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 277.3238

Ref: IN-DA003440

6-Methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine

CAS: 152460-10-1

6-Methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine

Purity: 98%

Molecular weight: 277.32g/mol

Ref: 54-OR345028

Imatinib EP Impurity F

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Color and Shape: Yellow Solid

Molecular weight: 277.33

Ref: 4Z-I-0913

Imatinib EP Impurity F

Controlled Product

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Color and Shape: Neat

Molecular weight: 277.32

Ref: 86-MM3566.06

Imatinib EP Impurity F

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Molecular weight: 277.32

Ref: ST-EA-CP-I5006

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

Controlled Product

CAS: 152460-10-1

Impurity Imatinib EP Impurity F
Applications N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine (Imatinib EP Impurity F) is a selective inhibitor of protein kinase C (PKC). It is a COVID19-related research product.
References Szczylik, C., et al.: Science, 253, 562 (1991), Geissler, J., et al.: Cancer Res., 52, 4492 (1992), Paul, R., et al.: J. Med. Chem., 36, 2716 (1993),

Formula: C₁₆H₁₅N₅

Color and Shape: Neat

Molecular weight: 277.32

Ref: TR-A618220

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS: 152460-10-1

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 277.33099365234375

Ref: 10-F080006

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS: 152460-10-1

Imatinib is an anticancer drug that belongs to the class of trimethyls. It is a potent inhibitor of tyrosine-specific protein kinases, including Bcr-Abl and Src family kinases. It has been shown to have antineoplastic properties in human cells in vitro. Imatinib is structurally similar to the anticancer agent lapatinib and inhibits G1 phase cell cycle progression by preventing phosphorylation of retinoblastoma protein (Rb). Imatinib is also genotoxic due to its structural similarity to other known genotoxic compounds such as bromo-2′-deoxyuridine and 2-chloroimidazole.

Formula: C₁₆H₁₅N₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 277.32 g/mol

Ref: 3D-FA15934

TLC9995-0188

CAS: 152460-10-1

Tyrosine-protein kinase ABL, IC50: 1500 nM

Formula: C₁₆H₁₅N₅

Color and Shape: Yellow Solid

Molecular weight: 277.331

Ref: TM-T116837