CAS 152551-75-2

1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone

CAS: 152551-75-2

Formula: C₁₉H₂₇N₅O₄

Color and Shape: Solid

Molecular weight: 389.4488

Ref: IN-DA00ADRI

Terazosin EP Impurity J

CAS: 152551-75-2

Formula: C₁₉H₂₇N₅O₄

Color and Shape: White To Off-White Solid

Molecular weight: 389.46

Ref: 4Z-T-753

1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone

Controlled Product

CAS: 152551-75-2

Impurity Terazosin EP Impurity J
Applications 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (Terazosin EP Impurity J) is an impurity of Terazosin (T105000), an α-1-adrenergic blocker that is related to Prazosin (P702325).
References Blom, Y., et al.: J. Chromatograph., 653, 138 (1993);

Formula: C₁₉H₂₇N₅O₄

Color and Shape: Neat

Molecular weight: 389.45

Ref: TR-A605030

1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone-d8

Controlled Product

CAS: 152551-75-2

Applications Isotope labelled 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone s an impurity of Terazosin (T105000), an α-1-adrenergic blocker that is related to Prazosin (P702325).
References Blom, Y., et al.: J. Chromatograph., 653, 138 (1993);

Formula: C₁₉D₈H₁₉N₅O₄

Color and Shape: Neat

Molecular weight: 397.498

Ref: TR-A605032

1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone

CAS: 152551-75-2

1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (DMPP) is an analog of the antiarrhythmic drugs flecainide and propafenone. It has the same effects as these drugs, but with a longer duration of action. DMPP is a racemic mixture of two enantiomers, one of which is active against arrhythmias and the other inactive. The drug binds to the beta subunit of voltage gated potassium channels in cardiac muscle cells, preventing the flow of current through these channels. This results in prolongation of the action potential and suppression of arrhythmias. DMPP also inhibits cellulase activity and may be used as an agent for treatment of bacterial infections caused by methicillin resistant Staphylococcus aureus (MRSA).

Formula: C₁₉H₂₇N₅O₄

Purity: Min. 95%

Molecular weight: 389.45 g/mol

Ref: 3D-IA63849

Terazosin EP Impurity J

CAS: 152551-75-2

Formula: C₁₉H₂₇N₅O₄

Molecular weight: 389.5

Ref: ST-EA-CP-T17010