CAS 152721-37-4

2-Nitro-N-(2,2,3,3,3-pentafluoropropyl)-1H-imidazole-1-acetamide

Description:

2-Nitro-N-(2,2,3,3,3-pentafluoropropyl)-1H-imidazole-1-acetamide is a chemical compound characterized by its imidazole ring, which is a five-membered heterocyclic structure containing two nitrogen atoms. The presence of a nitro group (-NO2) at the 2-position of the imidazole ring contributes to its reactivity and potential applications in various chemical reactions. The compound also features a pentafluoropropyl group, which is notable for its high fluorine content, imparting unique properties such as increased lipophilicity and thermal stability. This fluorinated moiety can enhance the compound's performance in biological systems and materials science. The acetamide functional group (-C(=O)NH2) provides additional hydrogen bonding capabilities, which may influence solubility and interaction with biological targets. Overall, this compound's distinctive structural features suggest potential utility in pharmaceuticals, agrochemicals, or as a building block in organic synthesis, although specific applications would depend on further research and evaluation.

Formula: C₈H₇F₅N₄O₃

InChI: InChI=1S/C8H7F5N4O3/c9-7(10,8(11,12)13)4-15-5(18)3-16-2-1-14-6(16)17(19)20/h1-2H,3-4H2,(H,15,18)

InChI key: InChIKey=JGGDSDPOPRWSCX-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1N(CC(NCC(C(F)(F)F)(F)F)=O)C=CN1

Synonyms:

• 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide
• NSC 684681
• EF 5
• 1H-Imidazole-1-acetamide, 2-nitro-N-(2,2,3,3,3-pentafluoropropyl)-
• 2-Nitro-N-(2,2,3,3,3-pentafluoropropyl)-1H-imidazole-1-acetamide
• EF5 >=98% (HPLC)

EF-5

CAS: 152721-37-4

EF-5 (2-Nitroimidazole) is a agent of hypoxia labeling. It is used to identify hypoxia in cells.

Formula: C₈H₇F₅N₄O₃

Purity: 98.26%

Color and Shape: Solid

Molecular weight: 302.16

Ref: TM-T15202

EF-5

CAS: 152721-37-4

EF-5

Purity: ≥98%

Molecular weight: 302.16g/mol

Ref: 54-BUP10410

EF-5

CAS: 152721-37-4

EF-5 is a cellular transforming agent that induces tumor formation in experimental animals. It is used to investigate the mechanism of hypoxic cell transformation, as well as for the treatment of infectious diseases. EF-5 has been shown to inhibit tumor growth by binding to DNA and inhibiting transcription and replication. EF-5 also stimulates the immune system by binding to human immunoglobulin G (IgG) and stimulating the production of antibodies against tumors. EF-5 binds to nucleic acids, including DNA, RNA, or single stranded DNA or RNA, with a high affinity and specificity. EF-5 is also used in radiation therapy for carcinoma cell lines.

Formula: C₈H₇F₅N₄O₃

Purity: Min. 95%

Molecular weight: 302.16 g/mol

Ref: 3D-CGA72137