CAS 152741-89-4

amythiamicin A

Description:

Amythiamicin A is a natural product classified as a member of the thiazole-containing antibiotics, specifically derived from the bacterium Amycolatopsis. It exhibits a complex molecular structure characterized by a thiazole ring and various functional groups that contribute to its biological activity. This compound is known for its potent antimicrobial properties, particularly against certain strains of bacteria and fungi, making it of interest in pharmaceutical research. Amythiamicin A operates through mechanisms that may involve inhibition of protein synthesis or interference with cellular processes in target organisms. Its unique structure and biological activity have prompted investigations into its potential applications in treating infections and as a lead compound for developing new antibiotics. Additionally, the compound's stability, solubility, and interaction with biological systems are important factors that influence its efficacy and therapeutic potential. As research continues, understanding the full range of its characteristics and mechanisms will be crucial for harnessing its benefits in medicinal chemistry.

Formula: C₅₀H₅₁N₁₅O₈S₆

InChI: InChI=1/C50H51N15O8S6/c1-20(2)35-48-61-31(19-78-48)46-57-27(15-75-46)38-23(9-10-24(54-38)45-60-30(18-76-45)43-56-26(14-73-43)50(72)65-11-7-8-32(65)39(51)68)44-58-29(17-74-44)41(70)55-25(12-33(66)52-6)47-64-37(22(5)79-47)42(71)63-36(21(3)4)49-59-28(16-77-49)40(69)53-13-34(67)62-35/h9-10,15-21,25-26,32,35-36H,7-8,11-14H2,1-6H3,(H2,51,68)(H,52,66)(H,53,69)(H,55,70)(H,62,67)(H,63,71)

Synonyms:

• 9H,16H-8,5:15,12:22,19:32,29:36,33-Pentanitrilo-5H,29H,33H-pyrido(3,2-al) (1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontine-11-acetamide, 10,11,17,18,23,24,25,26,27,28-decahydro-2-(4-(4-((2-(aminocarbonyl)-1-pyrrolidinyl)carbonyl)-4,5-dihydro-2-oxalyl)-2-thiazolyl)-18,28-(bis(1-methylethyl)-N,14-dimethyl-
• 1-{[2-(2-{21-methyl-18-[2-(methylamino)-2-oxoethyl]-16,23,30,33-tetraoxo-25,35-di(propan-2-yl)-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decaazaheptacyclo[34.2.1.1~2,5~.1~12,15~.1~19,22~.1~26,29~.0~6,11~]tritetraconta-1(38),2(43),4,6,8,10,12(42),14,19(41),21,26(40),28,36(39)-tridecaen-8-yl}-1,3-thiazol-4-yl)-4,5-dihydro-1,3-oxazol-4-yl]carbonyl}pyrrolidine-2-carboxamide (non-preferred name)
• Amythiamicin A
• 9H,16H-8,5:15,12:22,19:32,29:36,33-Pentanitrilo-5H,29H,33H-pyrido[3,2-a1][1,11,18,25,31,4,7,14,21]pentathiatetraazacyclotetratriacontine-11-acetamide, 2-[4-[4-[[2-(aminocarbonyl)-1-pyrrolidinyl]carbonyl]-4,5-dihydro-2-oxazolyl]-2-thiazolyl]-10,11,17,18,23,24,25,26,27,28-decahydro-N,14-dimethyl-18,28...

Amythiamicin A

CAS: 152741-89-4

Amythiamicin A is an antibiotic effective against gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), and exhibits activity against Plasmodium falciparum.

Formula: C₅₀H₅₁N₁₅O₈S₆

Color and Shape: Solid

Molecular weight: 1182.43

Ref: TM-TN9093