CAP-18, also known as rabbit CAP-18, is a peptide derived from the cathelicidin family, which plays a crucial role in the innate immune response. This substance is characterized by its antimicrobial properties, exhibiting activity against a range of pathogens, including bacteria, fungi, and viruses. CAP-18 is typically composed of a sequence of amino acids that contribute to its ability to disrupt microbial membranes, leading to cell lysis. Additionally, it has been studied for its potential role in wound healing and inflammation regulation. The peptide is produced in various tissues, particularly in response to infection or injury, highlighting its importance in the host defense mechanism. Its structure often includes a hydrophobic region that facilitates interaction with lipid membranes, enhancing its antimicrobial efficacy. Research into CAP-18 continues to explore its therapeutic applications, particularly in developing new antimicrobial agents and understanding its role in immune modulation.

CAP - 18, rabbit

152742-15-9: CAP-18, also known as rabbit CAP-18, is a peptide derived from the cathelicidin family, which plays a crucial role in the innate immune response. This substance is characterized by its antimicrobial properties, exhibiting activity against a range of pathogens, including bacteria, fungi, and viruses. CAP-18 is typically composed of a sequence of amino acids that contribute to its ability to disrupt microbial membranes, leading to cell lysis. Additionally, it has been studied for its potential role in wound healing and inflammation regulation. The peptide is produced in various tissues, particularly in response to infection or injury, highlighting its importance in the host defense mechanism. Its structure often includes a hydrophobic region that facilitates interaction with lipid membranes, enhancing its antimicrobial efficacy. Research into CAP-18 continues to explore its therapeutic applications, particularly in developing new antimicrobial agents and understanding its role in immune modulation.

<p>CAP18, a 37-residue rabbit peptide, combats Gram-positive (IC50: 130-200 nM) and Gram-negative (IC50: 20-100 nM) bacteria, aiding sepsis research.</p>

CAS 152742-15-9

CAP - 18, rabbit

CAP18 (rabbit)

Ref: TM-T39009