CAS 152751-57-0: Sevelamer hydrochloride

Description: Sevelamer hydrochloride is a polymeric compound primarily used as a phosphate binder in patients with chronic kidney disease who are on dialysis. It functions by binding dietary phosphate in the gastrointestinal tract, thereby reducing its absorption and helping to manage hyperphosphatemia. The substance is characterized by its high molecular weight and is non-absorbed, which means it does not enter systemic circulation. Sevelamer hydrochloride is typically administered orally in tablet or powder form and is known for its ability to lower serum phosphate levels without causing calcium overload, making it a preferred choice over calcium-based binders. Additionally, it has been associated with potential benefits in lipid profiles, as it may help lower LDL cholesterol levels. The compound is stable under normal conditions but should be stored in a cool, dry place to maintain its efficacy. As with any medication, it is essential to monitor for potential side effects, including gastrointestinal issues, and to adjust dosages as necessary based on individual patient needs.

Formula: (C₃H₇N·C₃H₅ClO·ClH)x

InChI: InChI=1S/C3H5ClO.C3H7N.ClH/c4-1-3-2-5-3;1-2-3-4;/h3H,1-2H2;2H,1,3-4H2;1H

InChI key: InChIKey=KHNXRSIBRKBJDI-UHFFFAOYSA-N

SMILES: Cl.ClCC1OC1.C=CCN

Synonyms:

• 2-Propen-1-amine, hydrochloride, polymer with (chloromethyl)oxirane
• Allylamine hydrochloride-epichlorhydrin copolymer
• Allylamine hydrochloride-epichlorohydrin copolymer
• 2-Propen-1-amine, hydrochloride (1:1), polymer with 2-(chloromethyl)oxirane
• Oxirane, (chloromethyl)-, polymer with 2-propen-1-amine hydrochloride

Sevelamer Hydrochloride

CAS: 152751-57-0

Polysulfides, polysulfones & oth products spec in note 3, chapter 39, except elastomeric

• Formula: (C₃H₇N)ab(C₉H₁₈N₂O)cn·xHCl
• Color and Shape: White Off-White Powder

2-Propen-1-amine, hydrochloride (1:1), polymer with 2-(chloromethyl)oxirane

CAS: 152751-57-0

• Formula: C₆H₁₂ClNO
• Color and Shape: Solid
• Molecular weight: 149.6186

Sevelamer HCl

CAS: 152751-57-0

• Color and Shape: Pale Yellow Solid

Sevelamer hydrochloride

CAS: 152751-57-0

Sevelamer hydrochloride

CAS: 152751-57-0

Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding …

• Formula: (C₃H₇N·C₃H₅ClO·HCl)x
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 186.08

Sevelamer Hydrochloride (Technical Grade)

CAS: 152751-57-0

Applications Sevelamer hydrochloride is a noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic …

• Formula: (C₃H₇N)m•(C₃H₅ClO)n•(HCl)x
• Color and Shape: Light Yellow

Sevelamer hydrochloride

CAS: 152751-57-0

Sevelamer is a binder that binds to phosphorus and decreases its absorption from the intestine. …

• Purity: Min. 95%