CAS 152764-26-6

Exemestane Impurity 21

CAS: 152764-26-6

Formula: C₂₀H₂₄O₃

Molecular weight: 312.41

Ref: 4Z-E-1941

Exemestane Impurity 21-d3

CAS: 152764-26-6

Formula: C₂₀H₂₁D₃O₃

Molecular weight: 315.43

Ref: 4Z-E-1943

6-Hydroxymethyl Exemestane

Controlled Product

CAS: 152764-26-6

Applications A potential metabolite of Exemestane (E957000).
References Buzzetti, F., et al.: Steroids, 58, 527 (1993),

Formula: C₂₀H₂₄O₃

Color and Shape: Neat

Molecular weight: 312.40

Ref: TR-H825510

6-Hydroxymethyl Exemestane-d3

Controlled Product

CAS: 152764-26-6

Formula: C₂₀D₃H₂₁O₃

Color and Shape: Neat

Molecular weight: 315.421

Ref: TR-H825512

6-Hydroxymethyl exemestane

Controlled Product

CAS: 152764-26-6

6-Hydroxymethyl exemestane is a form of the drug exemestane, which is a synthetic aromatase inhibitor. It has been approved for use in postmenopausal women with estrogen receptor (ER) positive breast cancer that has progressed after tamoxifen therapy. 6-Hydroxymethyl exemestane inhibits the production of estrogen by inhibiting the enzyme aromatase, which is responsible for converting androgens to estrogens. This inhibition leads to decreased tumor progression and development. 6-Hydroxymethyl exemestane binds to the heme group at the active site of aromatase, thereby blocking its activity and preventing conversion of androgens to estrogens. This prevents the synthesis of estrogen, which may be responsible for breast cancer growth.

Formula: C₂₀H₂₄O₃

Purity: Min. 95%

Color and Shape: Off-White To Light (Or Pale) Yellow Solid

Molecular weight: 312.4 g/mol

Ref: 3D-FH24388

6-Hydroxymethyl Exemestane

CAS: 152764-26-6

Formula: C₂₀H₂₄O₃

Molecular weight: 312.41

Ref: ST-EA-CP-E45012