CAS 152831-36-2

α-Hydroxy-α-phosphono-3-pyridinepropanoic acid

Description:

α-Hydroxy-α-phosphono-3-pyridinepropanoic acid, with the CAS number 152831-36-2, is a chemical compound that features a pyridine ring, a phosphono group, and a hydroxyl group, contributing to its unique properties. This compound is characterized by its ability to act as a phosphonate, which can participate in various chemical reactions, particularly in the context of biological systems. The presence of the hydroxyl group enhances its solubility in polar solvents, making it more bioavailable. Additionally, the pyridine moiety can engage in hydrogen bonding and π-π interactions, influencing its reactivity and interaction with other molecules. This compound is of interest in medicinal chemistry and agricultural applications, particularly as a potential herbicide or in the development of pharmaceuticals. Its structural features suggest that it may exhibit specific biological activities, although detailed studies would be necessary to elucidate its mechanisms of action and potential therapeutic uses. Overall, α-Hydroxy-α-phosphono-3-pyridinepropanoic acid represents a versatile compound with significant implications in various fields of research.

Formula: C₈H₁₀NO₆P

InChI: InChI=1S/C8H10NO6P/c10-7(11)8(12,16(13,14)15)4-6-2-1-3-9-5-6/h1-3,5,12H,4H2,(H,10,11)(H2,13,14,15)

InChI key: InChIKey=FJVYPXVLXQXDHM-UHFFFAOYSA-N

SMILES: C(CC=1C=CC=NC1)(P(=O)(O)O)(C(O)=O)O

Synonyms:

• 2-Hydroxy-2-phosphono-3-(pyridin-3-yl)propanoic acid
• 3-Pyridinepropanoic acid, α-hydroxy-α-phosphono-
• 3Pehpc
• Ne-10790
• α-Hydroxy-α-phosphono-3-pyridinepropanoic acid
• NE10790

NE 10790

CAS: 152831-36-2

NE 10790, similar to risedronate, is a mild bone resorption inhibitor but poorly blocks FPP synthase.

Formula: C₈H₁₀NO₆P

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 247.14

Ref: TM-T16289

NE 10790

CAS: 152831-36-2

Formula: C₈H₁₀NO₆P

Purity: 99%

Color and Shape: Solid

Molecular weight: 247.1419

Ref: IN-DA01FPM9

NE 10790

CAS: 152831-36-2

NE 10790

Purity: ≥95%

Molecular weight: 247.14g/mol

Ref: 54-BUP02119

3-PEHPC

Controlled Product

CAS: 152831-36-2

Applications 3-PEHPC is a phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase and is used in antiosteoporotic drugs.
References Coxon, F. et al.: Eur. J. Med. Chem., 84, 77 (2014); Kazmierczak, A. et al.: J. Med. Chem., 60, 8781 (2000);

Formula: C₈H₁₀NO₆P

Color and Shape: Neat

Molecular weight: 247.142

Ref: TR-P188695

2-HYDROXY-2-PHOSPHONO-3-(PYRIDIN-3-YL)PROPANOIC ACID

CAS: 152831-36-2

Purity: 99%

Molecular weight: 247.1430054

Ref: 10-F840864

NE 10790

CAS: 152831-36-2

NE 10790 is a chemical compound that inhibits angiogenesis by targeting the hydroxyl group on the tyrosine residue in vascular endothelial growth factor receptor-2. NE 10790 has been found to have antiangiogenic properties and to suppress autophagy. This drug has also been shown to inhibit prostate cancer cell proliferation and viability, as well as skin cancer cell proliferation and viability. NE 10790 is being investigated as a potential treatment for bone cancer and other forms of cancer, such as breast cancer. The molecular docking analysis of NE 10790 with the VEGFR-2 protein has shown that this drug binds to the binding pocket of the VEGFR-2 protein and blocks its interaction with VEGF-A.

Formula: C₈H₁₀NO₆P

Purity: Min. 95%

Molecular weight: 247.02457

Ref: 3D-BN178035