CAS 15291-77-7
:Ginkgolide B
Description:
Ginkgolide B is a natural compound derived from the leaves of the Ginkgo biloba tree, known for its potential therapeutic properties. It belongs to a class of compounds called terpenoids, specifically a type of ginkgolide, which are unique to Ginkgo species. Ginkgolide B is characterized by its complex bicyclic structure, which contributes to its biological activity. It exhibits various pharmacological effects, including neuroprotective, anti-inflammatory, and antioxidant properties, making it of interest in the study of neurodegenerative diseases and cognitive enhancement. Additionally, Ginkgolide B has been investigated for its ability to inhibit platelet-activating factor (PAF), which plays a role in inflammation and thrombosis. The compound is typically studied in the context of herbal medicine and dietary supplements, often marketed for improving memory and circulation. However, its efficacy and safety profile require further research to fully understand its potential benefits and risks in clinical applications.
Formula:C20H24O10
InChI:InChI=1/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9-,10+,11+,15+,17?,18?,19-,20-/m1/s1
InChI key:InChIKey=SQOJOAFXDQDRGF-MAGGBRLHSA-N
SMILES:O[C@@H]1C23C4([C@]5(O)[C@]1(OC(=O)[C@H]5C)[H])O[C@]6(C2([C@H](C(C)(C)C)C[C@]3(OC4=O)[H])[C@@H](O)C(=O)O6)[H]
Synonyms:- (1R,3R,6R,8S,10R,12S,13S,16S,17R)-6,12,17-Trihydroxy-16-methyl-8-(2-methyl-2-propanyl)-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecan-5,15,18-trion
- (1R,3R,6R,8S,10R,12S,13S,16S,17R)-6,12,17-Trihydroxy-16-methyl-8-(2-methyl-2-propanyl)-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
- (1R,3R,6R,8S,10R,12S,13S,16S,17R)-8-tert-Butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
- (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione
- (1R,3aR,4aR,4bR,5S,7aS,8S,9R,11S)-11-tert-butyl-1,4b,8-trihydroxy-5-methyltetrahydro-4bH,9H-9,4a-(epoxymethano)cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1H,5H)-trione
- (1b)-1-Hydroxyginkgolide A
- 5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-α<sup>5a</sup>,1,2,3,5,8-hexahydroxy-α<sup>3</sup>-methyl-, tri-γ-lactone
- 6H-9,4a-(epoxymethano)-3aH,9H-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1H)-trione, 11-(1,1-dimethylethyl)hexahydro-1,4b,8-trihydroxy-5-methyl-, (1R,3aR,4aR,4bR,5S,7aS,8S,9R,11S)-
- 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-
- 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-, [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11β,11aR*)]-
- Bilobalide B
- Bn 52021
- Bn 52051
- Ginkgolide A, 1-hydroxy-, (1β)-
- Ginkgolide B
- Ginkgolides, ginkgolide B
- 5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-α5a,1,2,3,5,8-hexahydroxy-α3-methyl-, tri-γ-lactone
- (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione
- ginkgolide B from ginkgo leaves
- ginkgolide b from ginkgo biloba leaves
- 7-DEOXYGINKGOLIDE C
- See more synonyms
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Found 12 products.
Ginkgolide B
CAS:Formula:C20H24O10Purity:>93.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:424.40Ginkgolide B
CAS:Ginkgolide B analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C20H24O10Purity:(HPLC) ≥98%Color and Shape:PowderMolecular weight:424.41Ginkgolide B
CAS:Ginkgolide B has potent neuroprotective, anti-arrhythmias, anti-inflammatory and anti-apoptotic effects, it might be a promising drug on inhibiting platelet function and reducing inflammation in atherosclerosis.Ginkgolide B retards the proliferation and development of mouse embryonic stem cells (ESCs) and blastocysts in vitro and causes developmental injury in vivo.Formula:C20H24O10Purity:95%~99%Molecular weight:424.402Ginkgolide B
CAS:Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.Formula:C20H24O10Purity:98.66% - 99.81%Color and Shape:White Crystal PowderMolecular weight:424.40Ginkgolide b
CAS:LactoneFormula:C20H24O10Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:424.41Ginkgolide B
CAS:Applications Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists.
References Korth, R., et al.: Eur. J. Pharmacol., 152, 101 (1988), Braquet, P., et al.: Med. Res. Rev., 11, 295 (1991), van Beek, T.A., et al.: Bioorg. Med. Chem., 13, 5001 (2005)Formula:C20H24O10Color and Shape:NeatMolecular weight:424.4Ginkgolide B
CAS:Ginkgolide B is a diterpenoid lactone, which is a secondary metabolite isolated from the leaves of the Ginkgo biloba tree. This compound is primarily sourced from the extract of Ginkgo biloba, a plant that has been utilized for centuries in traditional medicine systems.
Formula:C20H24O10Purity:Min. 90 Area-%Color and Shape:White PowderMolecular weight:424.4 g/molRef: 3D-FG10334
Discontinued product
