CAS 15307-78-5
:Diclofenac methyl ester
Description:
Diclofenac methyl ester, with the CAS number 15307-78-5, is an ester derivative of diclofenac, a non-steroidal anti-inflammatory drug (NSAID) commonly used for its analgesic and anti-inflammatory properties. This compound typically appears as a white to off-white crystalline solid and is characterized by its moderate solubility in organic solvents such as ethanol and methanol, while being less soluble in water. The chemical structure features a methyl ester functional group, which influences its pharmacokinetic properties, potentially enhancing its absorption and bioavailability compared to its parent compound, diclofenac. Diclofenac methyl ester is primarily studied for its potential therapeutic applications, including pain relief and inflammation reduction. Additionally, it may exhibit different pharmacological profiles and side effects compared to diclofenac, making it a subject of interest in medicinal chemistry. As with many NSAIDs, caution is advised regarding its use, particularly in individuals with a history of gastrointestinal issues or cardiovascular conditions.
Formula:C15H13Cl2NO2
InChI:InChI=1S/C15H13Cl2NO2/c1-20-14(19)9-10-5-2-3-8-13(10)18-15-11(16)6-4-7-12(15)17/h2-8,18H,9H2,1H3
InChI key:InChIKey=VETACGBDFVVKGZ-UHFFFAOYSA-N
SMILES:N(C1=C(CC(OC)=O)C=CC=C1)C2=C(Cl)C=CC=C2Cl
Synonyms:- 2-[2-(2,6-Dichloroanilino)phenyl]acetate
- Acetic acid, [o-(2,6-dichloroanilino)phenyl]-, methyl ester
- Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, methyl ester
- Diclofenac Me
- Diclofenac, methylated
- Methyl 2-(2,6-dichloroanilino)phenylacetate
- Methyl [2-(2,6-dichloroanilino)phenyl]acetate
- Methyl {2-[(2,6-Dichlorophenyl)Amino]Phenyl}Acetate
- [o-(2,6-Dichloroanilino)phenyl]acetic acid methyl ester
- Diclofenac methyl ester
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Found 13 products.
Methyl 2-(2,6-Dichloroanilino)phenylacetate
CAS:Formula:C15H13Cl2NO2Purity:>97.0%(GC)(N)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:310.17Diclofenac Methyl Ester (Methyl 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetate)
CAS:<p>Aromatic amino-acids and their esters, other than those containing more than one kind of oxygen function, nesoi</p>Formula:C15H13Cl2NO2Color and Shape:White Crystalline PowderMolecular weight:309.03233Diclofenac Methyl Ester
CAS:Formula:C15H13Cl2NO2Purity:97%Color and Shape:SolidMolecular weight:310.1752Aceclofenac EP Impurity B
CAS:Formula:C15H13Cl2NO2Color and Shape:White To Off-White SolidMolecular weight:310.17Methyl 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetate (Methyl Ester of Diclofenac)
CAS:Controlled ProductFormula:C15H13Cl2NO2Color and Shape:NeatMolecular weight:310.18Diclofenac methyl ester
CAS:<p>Diclofenac methyl ester: a hydrophobic NSAID prodrug, more soluble but toxic in isopropylmyristate than diclofenac acid.</p>Formula:C15H13Cl2NO2Purity:98.04%Color and Shape:SolidMolecular weight:310.18Diclofenac Methyl Ester
CAS:Controlled Product<p>Impurity Aceclofenac EP Impurity B<br>Applications Diclofenac Methyl Ester is the methyl ester analogue of Diclofenac (D436450), a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Aceclofenac EP Impurity B<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dannhardt, G., et al.: Eur. J. Med. Chem., 36, 109 (2001), Sorbera, L., et al.: Drug Future, 26, 133 (2001), Sorbera, L., et al.: Drug Future, 26, 133 (2001),<br></p>Formula:C15H13Cl2NO2Color and Shape:NeatMolecular weight:310.18Diclofenac methyl ester
CAS:<p>Diclofenac is a nonsteroidal anti-inflammatory drug that inhibits the enzyme cyclooxygenase. It is used to treat pain, inflammation, and stiffness from osteoarthritis and rheumatoid arthritis. Diclofenac methyl ester (DMEP) is a metabolite of diclofenac that can be found in human plasma samples. DMEP has been shown to have reactive properties, which may lead to the formation of oxidation products such as nitrites. DMEP also undergoes chemical degradation when exposed to organic solvents such as ethanol, acetone, and benzene.</p>Formula:C15H13Cl2NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:310.17 g/mol
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