CAS 15307-78-5

Diclofenac methyl ester

Description:

Diclofenac methyl ester, with the CAS number 15307-78-5, is an ester derivative of diclofenac, a non-steroidal anti-inflammatory drug (NSAID) commonly used for its analgesic and anti-inflammatory properties. This compound typically appears as a white to off-white crystalline solid and is characterized by its moderate solubility in organic solvents such as ethanol and methanol, while being less soluble in water. The chemical structure features a methyl ester functional group, which influences its pharmacokinetic properties, potentially enhancing its absorption and bioavailability compared to its parent compound, diclofenac. Diclofenac methyl ester is primarily studied for its potential therapeutic applications, including pain relief and inflammation reduction. Additionally, it may exhibit different pharmacological profiles and side effects compared to diclofenac, making it a subject of interest in medicinal chemistry. As with many NSAIDs, caution is advised regarding its use, particularly in individuals with a history of gastrointestinal issues or cardiovascular conditions.

Formula: C₁₅H₁₃Cl₂NO₂

InChI: InChI=1S/C15H13Cl2NO2/c1-20-14(19)9-10-5-2-3-8-13(10)18-15-11(16)6-4-7-12(15)17/h2-8,18H,9H2,1H3

InChI key: InChIKey=VETACGBDFVVKGZ-UHFFFAOYSA-N

SMILES: N(C1=C(CC(OC)=O)C=CC=C1)C2=C(Cl)C=CC=C2Cl

Synonyms:

• 2-[2-(2,6-Dichloroanilino)phenyl]acetate
• Acetic acid, [o-(2,6-dichloroanilino)phenyl]-, methyl ester
• Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, methyl ester
• Diclofenac Me
• Diclofenac, methylated
• Methyl 2-(2,6-dichloroanilino)phenylacetate
• Methyl [2-(2,6-dichloroanilino)phenyl]acetate
• Methyl {2-[(2,6-Dichlorophenyl)Amino]Phenyl}Acetate
• [o-(2,6-Dichloroanilino)phenyl]acetic acid methyl ester
• Diclofenac methyl ester

Methyl 2-(2,6-Dichloroanilino)phenylacetate

CAS: 15307-78-5

Formula: C₁₅H₁₃Cl₂NO₂

Purity: >97.0%(GC)(N)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 310.17

Ref: 3B-M2903

Diclofenac Methyl Ester

CAS: 15307-78-5

Color and Shape: Neat

Ref: 61-FOR0006.10

Diclofenac Methyl Ester (Methyl 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetate)

CAS: 15307-78-5

Aromatic amino-acids and their esters, other than those containing more than one kind of oxygen function, nesoi

Formula: C₁₅H₁₃Cl₂NO₂

Color and Shape: White Crystalline Powder

Molecular weight: 309.03233

Ref: 45-1A10370

Diclofenac Methyl Ester

CAS: 15307-78-5

Formula: C₁₅H₁₃Cl₂NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 310.1752

Ref: IN-DA00AOUN

Diclofenac methyl ester

CAS: 15307-78-5

Diclofenac methyl ester

Purity: ≥98%

Molecular weight: 310.18g/mol

Ref: 54-BUP11092

Aceclofenac EP Impurity B

CAS: 15307-78-5

Formula: C₁₅H₁₃Cl₂NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 310.17

Ref: 4Z-A-385

Methyl 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetate (Methyl Ester of Diclofenac)

Controlled Product

CAS: 15307-78-5

Formula: C₁₅H₁₃Cl₂NO₂

Color and Shape: Neat

Molecular weight: 310.18

Ref: 86-MM0006.10

Diclofenac methyl ester

CAS: 15307-78-5

Diclofenac methyl ester: a hydrophobic NSAID prodrug, more soluble but toxic in isopropylmyristate than diclofenac acid.

Formula: C₁₅H₁₃Cl₂NO₂

Purity: 98.04%

Color and Shape: Solid

Molecular weight: 310.18

Ref: TM-T37482

Aceclofenac EP impurity B

CAS: 15307-78-5

Formula: C₁₅H₁₃Cl₂NO₂

Molecular weight: 310.18

Ref: ST-EA-CP-A31002

Diclofenac Methyl Ester

Controlled Product

CAS: 15307-78-5

Impurity Aceclofenac EP Impurity B
Applications Diclofenac Methyl Ester is the methyl ester analogue of Diclofenac (D436450), a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Aceclofenac EP Impurity B
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dannhardt, G., et al.: Eur. J. Med. Chem., 36, 109 (2001), Sorbera, L., et al.: Drug Future, 26, 133 (2001), Sorbera, L., et al.: Drug Future, 26, 133 (2001),

Formula: C₁₅H₁₃Cl₂NO₂

Color and Shape: Neat

Molecular weight: 310.18

Ref: TR-D436500

Diclofenac Methyl Ester

CAS: 15307-78-5

Formula: C₁₅H₁₃Cl₂NO₂

Molecular weight: 310.18

Ref: ST-EA-CP-D20007

Diclofenac methyl ester

CAS: 15307-78-5

Diclofenac is a nonsteroidal anti-inflammatory drug that inhibits the enzyme cyclooxygenase. It is used to treat pain, inflammation, and stiffness from osteoarthritis and rheumatoid arthritis. Diclofenac methyl ester (DMEP) is a metabolite of diclofenac that can be found in human plasma samples. DMEP has been shown to have reactive properties, which may lead to the formation of oxidation products such as nitrites. DMEP also undergoes chemical degradation when exposed to organic solvents such as ethanol, acetone, and benzene.

Formula: C₁₅H₁₃Cl₂NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 310.17 g/mol

Ref: 3D-FD21713

Methyl 2-(2,6-Dichloroanilino)phenylacetate

CAS: 15307-78-5

Purity: 97%

Molecular weight: 310.1700134

Ref: 10-F876040