CAS 15307-86-5

Diclofenac

Description:

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. It is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, compounds involved in inflammation and pain signaling. Diclofenac is typically administered in various forms, including oral tablets, topical gels, and injections, making it versatile for treating conditions such as arthritis, muscle pain, and postoperative pain. The substance is known for its relatively rapid onset of action and effectiveness in managing acute and chronic pain. However, it may also be associated with gastrointestinal side effects, cardiovascular risks, and potential kidney issues, particularly with long-term use. Its chemical structure features a phenylacetic acid derivative, contributing to its pharmacological properties. Diclofenac is widely prescribed, but its use should be monitored to mitigate adverse effects, especially in patients with pre-existing health conditions.

Formula: C₁₄H₁₁Cl₂NO₂

InChI: InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)

InChI key: InChIKey=DCOPUUMXTXDBNB-UHFFFAOYSA-N

SMILES: N(C1=C(CC(O)=O)C=CC=C1)C2=C(Cl)C=CC=C2Cl

Synonyms:

• 1-(2,6-Dichlorophenyl)-1,3-dihydro-indole-2-one
• 1-(2,6-dichlorophenyl)-1,3-dihydro-2H-indol-2-one
• 2-((2,6-Dichlorophenyl)Amino)Benzeneacetic Acid
• 2-(2,6-Dichloroanilino)phenylacetic acid
• 2-(2,6-Dichlorophenylamino)phenylacetic acid
• 2-[2-(2,6-Dichloroanilino)phenyl]acetic acid
• 2-[2-(2,6-Dichlorophenylamino)phenyl]acetic acid
• Acetic acid, [o-(2,6-dichloroanilino)phenyl]-
• Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-
• Dcf 100C
• Dichlofenac
• Diclac
• Diclofenac Acid
• Diclofenaco
• Diclofenamic acid
• Dicloftil
• Diclomelan
• Dicloreuma
• Flector
• Flector EP Tissugel
• N-(2,6-Dichlorophenyl)-o-aminophenylacetic acid
• Ortofen
• Pennsaid
• Transfenac
• Vetagesic
• Voltaflan
• Voltaren Dolo
• Zolterol
• Zorvolex

2-(2,6-Dichloroanilino)phenylacetic Acid

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 296.15

Ref: 3B-D3748

Diclofenac Sodium Salt

CAS: 15307-79-6, 15307-86-5

Formula: C₁₄H₁₀Cl₂NNaO₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 318.13

Ref: 3B-D2508

2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.1486

Ref: IN-DA0038A0

Diclofenac

CAS: 15307-86-5

Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.

Formula: C₁₄H₁₁Cl₂NO₂

Purity: 99.69% - 99.97%

Color and Shape: Crystals From Ether-Petroleum Ether Solid

Molecular weight: 296.15

Ref: TM-T0196

Diclofenac (Aceclofenac EP Impurity A)

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 296.15

Ref: 4Z-D-065

Diclofenac

CAS: 15307-86-5

Diclofenac

Purity: ≥98%

Molecular weight: 296.15g/mol

Ref: 54-BUP18310

2-(2,6-Dichloroanilino)Phenylacetic Acid

CAS: 15307-86-5

2-(2,6-Dichloroanilino)Phenylacetic Acid

Purity: 98%

Molecular weight: 296.15g/mol

Ref: 54-OR1030293

Diclofenac, free acid

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Purity: ≥ 98.0% (dried basis)

Color and Shape: White to off-white or pale yellow-beige powder

Molecular weight: 296.15

Ref: 7W-GX8255

Diclofenac acid 100 µg/mL in Acetonitrile

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: Single Solution

Molecular weight: 296.15

Ref: 04-A12537000AL-100

Diclofenac 1000 µg/mL in Acetonitrile

Controlled Product

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: Single Solution

Molecular weight: 296.15

Ref: 04-A12537000AL-1000

Diclofenac acid

Controlled Product

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: Neat

Molecular weight: 296.15

Ref: 04-C12537000

2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetic Acid (Diclofenac)

CAS: 15307-86-5

Color and Shape: Off-White

Ref: 86-MM0006.20

Diclofenac Acid

CAS: 15307-86-5

Impurity Aceclofenac EP Impurity A
Applications Diclofenac acid is a nonsteroidal anti-inflammatory compound and decycloxygenase (COX) inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yagi, K., et. al.: Biol. Pharm. Bull., 37, 1234 (2014); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009)

Formula: C₁₄H₁₁Cl₂NO₂

Color and Shape: Off-White

Molecular weight: 296.15

Ref: TR-D436465

Aceclofenac EP Impurity A

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Molecular weight: 296.15

Ref: ST-EA-CP-A31001

2-(2-((2,6-Dichlorophenyl)amino)phenyl)acetic acid

CAS: 15307-86-5

Formula: C₁₄H₁₁Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.15

Ref: 10-F224122

Diclofenac free acid

CAS: 15307-86-5

COX inhibitor; non-steroidal anti-inflammatory drug

Formula: C₁₄H₁₁Cl₂NO₂

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 296.15 g/mol

Ref: 3D-FD30611