CAS 15307-93-4

2,6-Dichloro-N-phenylbenzenamine

Description:

2,6-Dichloro-N-phenylbenzenamine, also known as 2,6-dichloroaniline, is an organic compound characterized by the presence of two chlorine atoms and an aniline group attached to a benzene ring. This compound typically appears as a solid at room temperature and is known for its pale yellow to light brown color. It is primarily used in the synthesis of dyes, pigments, and pharmaceuticals due to its reactivity and ability to undergo various chemical transformations. The presence of chlorine substituents enhances its electrophilic properties, making it useful in electrophilic aromatic substitution reactions. Additionally, 2,6-Dichloro-N-phenylbenzenamine may exhibit moderate toxicity, necessitating careful handling and appropriate safety measures in laboratory and industrial settings. Its solubility in organic solvents, coupled with limited water solubility, influences its applications in organic synthesis. As with many chlorinated compounds, environmental considerations regarding its persistence and potential bioaccumulation are important in assessing its overall impact.

Formula: C₁₂H₉Cl₂N

InChI: InChI=1S/C12H9Cl2N/c13-10-7-4-8-11(14)12(10)15-9-5-2-1-3-6-9/h1-8,15H

InChI key: InChIKey=HDUUZPLYVVQTKN-UHFFFAOYSA-N

SMILES: N(C1=C(Cl)C=CC=C1Cl)C2=CC=CC=C2

Synonyms:

• 2,6-Dichloro Diphenylamine
• 2,6-Dichloro-N-phenylbenzenamine
• 2,6-dichloro-N-phenylaniline
• Benzenamine, 2,6-dichloro-N-phenyl-
• Decarboxymethyl diclofenac
• Diphenylamine, 2,6-dichloro-
• N-(2,6-Dichlorophenyl)-N-phenylamine
• N-(2,6-Dichlorophenyl)aniline
• N-Phenyl-2,6-dichloroaniline
• 2,6-Dichlorodiphenylamine

2,6-Dichlorodiphenylamine

CAS: 15307-93-4

Formula: C₁₂H₉Cl₂N

Purity: >98.0%(GC)

Color and Shape: White to Amber to Dark green powder to crystal

Molecular weight: 238.11

Ref: 3B-D3778

2,6-Dichlorodiphenylamine

CAS: 15307-93-4

Color and Shape: Neat

Ref: 61-FOR0006.15

2,6-Dichlorodiphenylamine

CAS: 15307-93-4

2,6-Dichlorodiphenylamine

Purity: ≥98%

Molecular weight: 238.11g/mol

Ref: 54-BUP19351

Diclofenac Impurity 1 (2,6-Dichlorodiphenylamine)

CAS: 15307-93-4

Formula: C₁₂H₉Cl₂N

Color and Shape: Pale Yellow Solid

Molecular weight: 238.11

Ref: 4Z-D-0616

2,6-Dichlorodiphenylamine

CAS: 15307-93-4

2,6-Dichlorodiphenylamine

Purity: 98%+

Molecular weight: 238.11g/mol

Ref: 54-OR1010166

2,6-Dichlorodiphenylamine

Controlled Product

CAS: 15307-93-4

Formula: C₁₂H₉Cl₂N

Color and Shape: Neat

Molecular weight: 238.11

Ref: 86-MM0006.15

N-(2,6-Dichlorophenyl)aniline

Controlled Product

CAS: 15307-93-4

Applications N-(2,6-Dichlorophenyl)aniline is an analog of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor.
References Moser, P. et al.: J. Med. Chem., 33, 2358 (1990); Encinas, S. et al.: Photochem. Photobiol., 68,640 (1998); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004), Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008), Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009),

Formula: C₁₂H₉Cl₂N

Color and Shape: White

Molecular weight: 238.11

Ref: TR-D434060

Diclofenac Desacetate Impurity

CAS: 15307-93-4

Formula: C₁₂H₉Cl₂N

Molecular weight: 238.11

Ref: ST-EA-CP-D20009

2,6-Dichloro-N-phenylaniline

CAS: 15307-93-4

Formula: C₁₂H₉Cl₂N

Purity: 98%

Color and Shape: Solid, White to greyish yellow green powder

Molecular weight: 238.11

Ref: 10-F239225

N-(2,6-Dichlorophenyl)aniline-13C6

Controlled Product

CAS: 15307-93-4

Applications N-(2,6-Dichlorophenyl)aniline-13C6 is an intermediate in the synthesis of Diclofenac-13C6 (D436449). Diclofenac-13C6 is a labelled analogue of Diclofenac Acid (D436465), which is a nonsteroidal anti-inflammatory compound and decycloxygenase (COX) inhibitor. Diclofenac-13C6 is also an intermediate in synthesizing Diclofenac-13C6 Sodium Salt (D436453), which is a labelled analogue of Diclofenac Sodium Salt (D436450).
References Yagi, K., et. al.: Biol. Pharm. Bull., 37, 1234 (2014); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004), Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009)

Formula: C₆C₆H₉Cl₂N

Color and Shape: Neat

Molecular weight: 244.069

Ref: TR-D434064

(2,6-Dichlorophenyl)phenylamine

CAS: 15307-93-4

2,6-Dichlorophenylphenylamine is a triazine compound that has been shown to inhibit the efflux pump in bladder cells. This inhibition leads to an increase in intracellular chloride concentrations and an increase in the amount of 2,6-dichlorophenylphenylamine that is retained by the cell. The 2,6-dichlorophenylphenylamine inhibits the production of prostaglandins and other inflammatory mediators by inhibiting cyclooxygenase enzymes in the arachidonic acid pathway. 2,6-Dichlorophenylphenylamine also inhibits prostaglandin synthesis by competing with AA for acylation reactions catalyzed by acyltransferase enzymes. This leads to a decrease in the production of substances such as leukotrienes and thromboxanes. 2,6-Dichlorophenylphenylamine may be used to treat eye disorders associated with

Formula: C₁₂H₉Cl₂N

Purity: Min. 95%

Molecular weight: 238.11 g/mol

Ref: 3D-FD133300

2,6-Dichlorodiphenylamine

CAS: 15307-93-4

2,6-Dichlorodiphenylamine shows activity against Candida albicans infections. 2,6-Dichlorodiphenylamine elevated the MIC by 4-fold of diclofenac sodium (DFNa).

Formula: C₁₂H₉Cl₂N

Purity: 99.81%

Color and Shape: Off White To Cream Coloured Crystalline Solid

Molecular weight: 238.11

Ref: TM-T38240

2,6-Dichlorodiphenylamine

CAS: 15307-93-4

Formula: C₁₂H₉Cl₂N

Color and Shape: Neat

Molecular weight: 238.11

Ref: 04-C12421700