CAS 153083-53-5

Paclitaxel IMpurity F

Description:

Paclitaxel Impurity F, with the CAS number 153083-53-5, is a chemical compound that is recognized as an impurity associated with the production of paclitaxel, a widely used chemotherapeutic agent. This impurity is characterized by its structural similarity to paclitaxel, which may affect the purity and efficacy of the final pharmaceutical product. Typically, impurities like Paclitaxel Impurity F are monitored during the manufacturing process to ensure compliance with regulatory standards. The compound may exhibit distinct physical and chemical properties, such as solubility in organic solvents and stability under specific conditions, which are critical for analytical characterization. Its presence can influence the pharmacokinetics and pharmacodynamics of paclitaxel, making it essential to quantify and control during drug formulation. Understanding the characteristics of such impurities is vital for ensuring the safety and effectiveness of cancer therapies that utilize paclitaxel.

Formula: C₄₇H₅₉NO₁₄

Synonyms:

• N-Debenzoyl-N-hexanoyl-N-methylpaclitaxel
• [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-[hexanoyl(methyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
• Benzenepropanoic acid, α-hydroxy-β-[methyl(1-oxohexyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• Paclitaxel EP Impurity F
• N-Methyltaxol C
• N-debenzoyl-N-hexanoyl-N-methylpclitaxel
• LJTMOSWWGSCCPR-AMMYIWEDSA-N
• Paclitaxel Impurity 6（Paclitaxel EP Impurity F）
• Paclitaxel IMpurity F
• N-Methyltaxol C(Paclitaxel EP Impurity F)
• Paclitaxel EP impurity F

Paclitaxel EP Impurity F

CAS: 153083-53-5

Formula: C₄₇H₅₉NO₁₄

Color and Shape: White To Off-White Solid

Molecular weight: 861.98

Ref: 4Z-P-2811

N-Methyltaxol C

CAS: 153083-53-5

N-methyltaxol C and paclitaxel boost heart muscle contractility but may cause arrhythmias and decrease coronary flow and heart pressure.

Formula: C₄₇H₅₉NO₁₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 861.982

Ref: TM-TN4616

N-Methyltaxol C

CAS: 153083-53-5

Formula: C₄₇H₅₉NO₁₄

Purity: 95%~99%

Molecular weight: 861.982

Ref: BP-SBP04278

N-Methyltaxol C

Controlled Product

CAS: 153083-53-5

Formula: C₄₇H₅₉NO₁₄

Color and Shape: Neat

Molecular weight: 861.97

Ref: TR-M330165

N-Methyltaxol C

CAS: 153083-53-5

N-Methyltaxol C is an amide derivative of the taxane family. It has been shown to increase systolic pressure in animal models and acts as a cardiac depressant. N-Methyltaxol C also has arrhythmogenic properties, which may be due to its ability to inhibit the inward flow of potassium ions through the cardiac membrane. This drug is being studied for its potential use in cancer treatment, specifically for cancer that arises from breast cells. N-Methyltaxol C has been shown to inhibit the growth of human breast cancer cells in vitro and to induce apoptosis in these cells. The mechanism by which it does this is not yet known, but it is thought that it may work by interfering with cell cycle progression or DNA synthesis by inhibiting protein synthesis or DNA replication.

Formula: C₄₇H₅₉NO₁₄

Purity: Min. 95%

Molecular weight: 861.97 g/mol

Ref: 3D-IM76714

Paclitaxel EP Impurity F

CAS: 153083-53-5

Formula: C₄₇H₅₉NO₁₄

Molecular weight: 861.98

Ref: ST-EA-CP-P36188