CAS 153088-76-7

Z-L-aspartic acid 4-tert-butyl ester 1-bromomethyl ketone

Description:

Z-L-aspartic acid 4-tert-butyl ester 1-bromomethyl ketone, with the CAS number 153088-76-7, is a chemical compound that features a combination of functional groups, including an amino acid derivative and a ketone. This compound is characterized by its Z-configuration, indicating a specific geometric arrangement around the double bond, which can influence its reactivity and biological activity. The presence of the tert-butyl ester group enhances its lipophilicity, potentially affecting its solubility and permeability in biological systems. The bromomethyl ketone moiety introduces a reactive site that can participate in various chemical reactions, making it useful in synthetic organic chemistry. Additionally, the compound may exhibit interesting pharmacological properties due to its structural features, which could be explored in medicinal chemistry. Overall, Z-L-aspartic acid 4-tert-butyl ester 1-bromomethyl ketone represents a versatile building block for further chemical transformations and applications in research and development.

Formula: C₁₇H₂₂BrNO₅

Synonyms:

• Z-Asp(OtBu)-bromomethyl ketone

Z-Asp(OtBu)-bromomethylketone

CAS: 153088-76-7

Intermediate for the synthesis of IL-1β converting enzyme (ICE, caspase-1) inhibitors or other inhibitors containing a C-terminal aspartyl residue modified by different methylketone derivatives. According to Németh el al., who detected an antiapoptotic activity for the compound itself, it may be used for studying the early events of apoptosis in some cell types.

Formula: C₁₇H₂₂BrNO₅

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 400.27

Ref: 01-4026186

tert-Butyl (S)-3-(((benzyloxy)carbonyl)amino)-5-bromo-4-oxopentanoate

CAS: 153088-76-7

tert-Butyl (S)-3-(((benzyloxy)carbonyl)amino)-5-bromo-4-oxopentanoate

Purity: 96%

Molecular weight: 400.27g/mol

Ref: 54-OR1065934

Z-Asp(OtBu)-bromomethyl ketone

CAS: 153088-76-7

Molecular weight: 400.26

Ref: 7W-GM2755

Z-Asp(OtBu)-bromomethylketone

CAS: 153088-76-7

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Formula: C₁₇H₂₂BrNO₅

Purity: Min. 95%

Molecular weight: 400.26 g/mol

Ref: 3D-FA111050