CAS 153168-05-9: PLECONARIL

Description: Pleconaril is an antiviral compound primarily known for its activity against enteroviruses and rhinoviruses, which are responsible for various respiratory infections. It functions by inhibiting viral replication, specifically targeting the viral capsid, thereby preventing the uncoating process necessary for viral entry into host cells. Pleconaril is characterized by its relatively low solubility in water, which can affect its bioavailability and formulation in pharmaceutical applications. The compound has a molecular weight that classifies it as a small molecule, and it exhibits a moderate lipophilicity, allowing for potential oral bioavailability. Its chemical structure includes a pyridine ring and a cyclopropane moiety, contributing to its unique pharmacological properties. While pleconaril has shown promise in clinical trials for treating viral infections, its use has been limited due to concerns about resistance and the need for further studies to establish its efficacy and safety profile in broader patient populations. Overall, pleconaril represents a significant area of interest in antiviral research, particularly for respiratory viral infections.

Formula: C₁₈H₁₈F₃N₃O₃

InChI: InChI=1S/C18H18F3N3O3/c1-10-7-13(16-22-17(27-24-16)18(19,20)21)8-11(2)15(10)25-6-4-5-14-9-12(3)23-26-14/h7-9H,4-6H2,1-3H3

InChI key: InChIKey=KQOXLKOJHVFTRN-UHFFFAOYSA-N

SMILES: FC(F)(F)C1=NC(=NO1)C=2C=C(C(OCCCC=3ON=C(C3)C)=C(C2)C)C

Synonyms:

• 1,2,4-Oxadiazole, 3-[3,5-dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-
• 3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
• 3-{3,5-Dimethyl-4-[3-(3-Methyl-1,2-Oxazol-5-Yl)Propoxy]Phenyl}-5-(Trifluoromethyl)-1,2,4-Oxadiazole
• Picovir
• Vp 63843
• Win 63843
• Pleconaril

Pleconaril

CAS: 153168-05-9

• Formula: C₁₈H₁₈F₃N₃O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 381.3490296

3-(3,5-Dimethyl-4-(3-(3-Methylisoxazol-5-Yl)Propoxy)Phenyl)-5-(Trifluoromethyl)-1,2,4-Oxadiazole

CAS: 153168-05-9

• Purity: 98%
• Molecular weight: 381.35g/mol

Pleconaril

CAS: 153168-05-9

• Purity: 99.88%
• Molecular weight: 381.35g/mol

Pleconaril-d4

CAS: 153168-05-9

• Formula: C₁₈H₁₄F₃N₃O₃D₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 385.38

Pleconaril

CAS: 153168-05-9

• Formula: C₁₈H₁₈F₃N₃O₃
• Color and Shape: Neat
• Molecular weight: 381.35

Pleconaril

CAS: 153168-05-9

Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is …

• Formula: C₁₈H₁₈F₃N₃O₃
• Purity: 98.21% - 99.09%
• Color and Shape: Solid
• Molecular weight: 381.35

Pleconaril-d6

CAS: 153168-05-9

• Formula: C₁₈H₁₄F₃N₃O₃D₆
• Molecular weight: 387.39

Pleconaril

CAS: 153168-05-9

• Formula: C₁₈H₁₈F₃N₃O₃
• Molecular weight: 381.36

Pleconaril

CAS: 153168-05-9

Applications Picornavirus replication inhibitor. Antiviral. Not a dangerous good if item is equal to or …

• Formula: C₁₈H₁₈F₃N₃O₃
• Color and Shape: Neat
• Molecular weight: 381.35

Pleconaril

CAS: 153168-05-9

• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 381.355010986328

Pleconaril

CAS: 153168-05-9

Anti-viral; capsid inhibitor

• Formula: C₁₈H₁₈F₃N₃O₃
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 381.35 g/mol

Pleconaril - Bio-X ™

CAS: 153168-05-9

This product is part of our Bio-X ™ Range. These products are aimed at life …

• Formula: C₁₈H₁₈F₃N₃O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 381.35 g/mol

Pleconaril

CAS: 153168-05-9

• Formula: C₁₈H₁₈F₃N₃O₃
• Color and Shape: Neat
• Molecular weight: 381.35