Indolizine-2-carbonitrile is a heterocyclic organic compound characterized by its unique indolizine structure, which consists of a five-membered ring containing two nitrogen atoms. This compound features a carbonitrile functional group (-C≡N) at the 2-position of the indolizine ring, contributing to its reactivity and potential applications in various chemical reactions. Indolizine derivatives are known for their biological activity, making them of interest in medicinal chemistry. The presence of the carbonitrile group enhances the compound's polarity and solubility in polar solvents, which can influence its interaction with biological targets. Additionally, indolizine-2-carbonitrile may exhibit fluorescence properties, making it useful in materials science and as a fluorescent probe. Its synthesis typically involves cyclization reactions, and it can serve as a building block for more complex molecules in organic synthesis. Overall, indolizine-2-carbonitrile is a versatile compound with potential applications in pharmaceuticals, agrochemicals, and materials science.

indolizine-2-carbonitrile

153274-67-0: Indolizine-2-carbonitrile is a heterocyclic organic compound characterized by its unique indolizine structure, which consists of a five-membered ring containing two nitrogen atoms. This compound features a carbonitrile functional group (-C≡N) at the 2-position of the indolizine ring, contributing to its reactivity and potential applications in various chemical reactions. Indolizine derivatives are known for their biological activity, making them of interest in medicinal chemistry. The presence of the carbonitrile group enhances the compound's polarity and solubility in polar solvents, which can influence its interaction with biological targets. Additionally, indolizine-2-carbonitrile may exhibit fluorescence properties, making it useful in materials science and as a fluorescent probe. Its synthesis typically involves cyclization reactions, and it can serve as a building block for more complex molecules in organic synthesis. Overall, indolizine-2-carbonitrile is a versatile compound with potential applications in pharmaceuticals, agrochemicals, and materials science.

<p>Indolizine-2-carbonitrile is a synthetic compound that has been shown to inhibit the replication of wild-type viruses, such as influenza A virus. It is an inhibitor of the enzyme RNA polymerase and prevents the transcription and replication of viral RNA. Indolizine-2-carbonitrile has been shown to be effective against resistant strains of influenza A virus by inhibiting the viral RNA polymerase. This drug also inhibits other non-nucleoside reverse transcriptases, such as HIV and HTLV, by binding to their active site. Indolizine-2-carbonitrile has optical properties that make it a potential candidate for use in optoelectronic devices.</p>

CAS 153274-67-0

indolizine-2-carbonitrile

Indolizine-2-carbonitrile

Ref: 3D-DGA27467