CAS 153322-05-5

Lanicemine

Description:

Lanicemine, with the CAS number 153322-05-5, is a chemical compound that belongs to the class of NMDA receptor antagonists. It is primarily investigated for its potential therapeutic applications in treating conditions such as depression and neuropathic pain. Lanicemine acts by modulating glutamatergic neurotransmission, which is crucial in various neuropsychiatric disorders. The compound is characterized by its ability to provide rapid antidepressant effects, distinguishing it from traditional antidepressants that often require weeks to show efficacy. Additionally, Lanicemine has been studied for its safety profile and tolerability in clinical settings. Its pharmacokinetic properties suggest a favorable absorption and distribution in the body, although specific details regarding its metabolism and excretion are still under investigation. Overall, Lanicemine represents a promising avenue in the development of novel treatments for mood disorders, with ongoing research aimed at fully elucidating its mechanisms of action and therapeutic potential.

Formula: C₁₃H₁₄N₂

InChI: InChI=1S/C13H14N2/c14-13(11-6-2-1-3-7-11)10-12-8-4-5-9-15-12/h1-9,13H,10,14H2/t13-/m0/s1

InChI key: InChIKey=FWUQWDCOOWEXRY-ZDUSSCGKSA-N

SMILES: [C@@H](CC1=CC=CC=N1)(N)C2=CC=CC=C2

Synonyms:

• (αS)-α-Phenyl-2-pyridineethanamine
• FPL 15896
• 2-Pyridineethanamine, α-phenyl-, (S)-
• 2-Pyridineethanamine, α-phenyl-, (αS)-
• ARL 15896

Lanicemine-d5 DiHCl

CAS: 153322-05-5, 153322-06-6

Formula: C₁₃H₉D₅N₂·2HCl

Molecular weight: 203.30 2*36.46

Ref: 4Z-L-174003

Lanicemine-d5

Controlled Product

CAS: 153322-05-5

Applications Lanicemine-d5 is the isotope labelled analog of Lanicemine (L173950); a non-selective voltage-dependant NMDA channel blocker. It is a potential anti-depressant which does not cause psychotomimetic activity and also a potential anti-hypertensive agent.
References Sanacora, G. et al.: Mol. Psych., 19, 978 (2014); O'Collins, V. et al.: J. Cerebral. Blood Flow Metab., 33, 1141 (2013)

Formula: C₁₃D₅H₉N₂

Color and Shape: Neat

Molecular weight: 203.294

Ref: TR-L173952

Lanicemine

Controlled Product

CAS: 153322-05-5

Applications Lanicemine is a non-selective voltage-dependant NMDA channel blocker. It is a potential anti-depressant which does not cause psychotomimetic activity. Potential anti-hypertensive agent.
References Sanacora, G. et al.: Mol. Psych., 19, 978 (2014); O'Collins, V. et al.: J. Cerebral. Blood Flow Metab., 33, 1141 (2013);

Formula: C₁₃H₁₄N₂

Color and Shape: Neat

Molecular weight: 198.264

Ref: TR-L173950

Lanicemine

CAS: 153322-05-5

Lanicemine is a low-trapping NMDA channel blocker. It also has a binding (Ki: 0.56-2.1 μM).

Formula: C₁₃H₁₄N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 198.26

Ref: TM-T15706