CAS 153408-27-6: azelastine hydrochloride

Description: Azelastine hydrochloride is a potent antihistamine primarily used in the treatment of allergic rhinitis and conjunctivitis. It functions as a selective H1 receptor antagonist, effectively blocking the action of histamine, a key mediator in allergic responses. This compound is characterized by its ability to provide rapid relief from allergy symptoms such as sneezing, itching, and nasal congestion. Azelastine hydrochloride is typically administered via nasal spray or eye drops, allowing for localized action with minimal systemic absorption. The substance is known for its relatively low solubility in water, which can influence its formulation in pharmaceutical products. Additionally, it exhibits a favorable safety profile, with common side effects being mild and transient. The chemical structure of azelastine includes a phthalazinone moiety, contributing to its pharmacological properties. Overall, azelastine hydrochloride is a valuable therapeutic agent in managing allergic conditions, offering both efficacy and convenience in administration.

Formula: C₂₂H₂₅Cl₂N₃O

InChI: InChI=1/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H/t18-;/m1./s1

Synonyms:

• 1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohydrochloride, (S)-
• 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride (1:1)

(S)-Azelastine HCl

CAS: 153408-27-6

• Formula: C₂₂H₂₅Cl₂N₃O
• Color and Shape: White To Off-White Solid
• Molecular weight: 418.36

(S)-Azelastine hydrochloride

CAS: 153408-27-6

(S)-Azelastine HCl, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.

• Formula: C₂₂H₂₅Cl₂N₃O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 418.36

(S)-Azelastine Hydrochloride

CAS: 153408-27-6

Applications Orally active H1-hystamine receptor antagonist. Antihistaminic. References Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 …

• Formula: C₂₂H₂₄ClN₃O·ClH
• Color and Shape: Neat
• Molecular weight: 418.36

(S)-Azelastine hydrochloride

CAS: 153408-27-6

Please enquire for more information about (S)-Azelastine hydrochloride including the price, delivery time and more …

• Formula: C₂₂H₂₅Cl₂N₃O
• Purity: Min. 95%
• Molecular weight: 418.36 g/mol