CAS 153437-78-6

Gefitinib Impurity 54

CAS: 153437-78-6

Formula: C₁₆H₁₃ClFN₃O₂

Color and Shape: Off-White Solid

Molecular weight: 333.75

Ref: 4Z-G-238

N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

CAS: 153437-78-6

Color and Shape: Neat

Ref: 86-MM3563.15

O-Desmorpholinopropyl-O-methyl-gefitinib

Controlled Product

CAS: 153437-78-6

Applications O-Desmorpholinopropyl-O-methyl-gefitinib is a anilinoquinazoline derivative of which acts as an inhibitor of tyrosine kinases and found to be allosteric inhibitors of the enzyme frutose 1,6-bisphosphatase. It serves as a lead to further drug design.
References Wright, S. W., Bioorganic & Medicinal Chemistry Letters, 11, 17-21, (2000)

Formula: C₁₆H₁₃ClFN₃O₂

Color and Shape: White To Off-White

Molecular weight: 333.74

Ref: TR-D296840

o-Desmorpholinopropyl-o-methyl-gefitinib

CAS: 153437-78-6

O-Desmorpholinopropyl-o-methyl-gefitinib is a cytotoxic drug that activates cancer cells. This compound has been shown to be reactive with colon cancer cells, inducing apoptosis and inhibiting the growth of cancer cells in vitro. O-Desmorpholinopropyl-o-methyl-gefitinib induces cell death in colon cancer cells by activating caspase 9 and caspase 3, which are enzymes that cleave proteins that activate other downstream effectors of apoptosis. O-Desmorpholinopropyl-o-methyl-gefitinib also inhibits the proliferation of human colorectal cancer cells (HCT116) and SW620 colon cancer cells.

Formula: C₁₆H₁₃ClFN₃O₂

Purity: Min. 95%

Molecular weight: 333.74 g/mol

Ref: 3D-DGA43778

O-Desmorpholinopropyl-O-methyl Gefitinib

CAS: 153437-78-6

Formula: C₁₆H₁₃ClFN₃O₂

Molecular weight: 333.75

Ref: ST-EA-CP-G14012