CAS 153439-40-8: Fexofenadine hydrochloride
Description:Fexofenadine hydrochloride is an antihistamine medication primarily used to alleviate allergy symptoms, such as hay fever and hives. It is classified as a second-generation antihistamine, which means it is less likely to cause sedation compared to first-generation antihistamines. The substance is a white to off-white crystalline powder that is soluble in water and exhibits a pH range of 4.5 to 6.5 in solution. Its molecular formula is C32H39NO4S, and it has a molecular weight of approximately 501.73 g/mol. Fexofenadine works by selectively blocking peripheral H1 receptors, thereby inhibiting the effects of histamine, a compound involved in allergic reactions. The drug is typically administered orally and is known for its rapid onset of action and prolonged duration of effect. Additionally, it has a favorable safety profile, with minimal interactions with other medications and a low incidence of side effects. Overall, fexofenadine hydrochloride is an effective option for managing allergic conditions.
Formula:C32H39NO4·ClH
InChI:InChI=1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H
InChI key:InChIKey=RRJFVPUCXDGFJB-UHFFFAOYSA-N
SMILES:Cl.O=C(O)C(C1=CC=C(C=C1)C(O)CCCN2CCC(CC2)C(O)(C=3C=CC=CC3)C=4C=CC=CC4)(C)C
- Synonyms:
- 2-(4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl)-2-methylpropanoic acid hydrochloride
- 2-[4-(1-Hydroxy-4-{4-[Hydroxy(Diphenyl)Methyl]Piperidin-1-Yl}Butyl)Phenyl]-2-Methylpropanoic Acid Hydrochloride (1:1)
- 2-[4-[1-Hydroxy-4-[4-(Hydroxy-Diphenyl-Methyl)-1-Piperidyl]-Butyl]Phenyl]-2-Methyl-Propanoic Acid Hydrochloride
- Alernex
- Allegra
- Alpha,Alpha-Dimethyl-4-[1-Hydroxy-4-[4-(Hydroxydiphenylmethyl)-1-Piperidinyl]Butyl]-Benzeneacetic Acid Hydrochloride
- Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride
- Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride (1:1)
- Carboxyterfenadine,Terfenadinecarboxylate
- Fastofen
- See more synonyms
- Feksine
- Fexadyne
- Fexodine
- Fexofen
- Fexofenadine HCl
- Fexofenadine-D10 Hcl
- Fexofendine Hcl
- Mdl 16455A
- Rapido
- Telfast
- Telfast BD
- Terfenidine Carboxylate Hydrochloride
- Vivafeks
- Α,Α-Dimethyl-4-[1-Hydroxy-4-[4-(Hydroxydiphenylmethyl)-1-Piperidinyl]Butyl]Benzeneacetic Acid
- Fexofenadine hydrochloride