CAS 153504-81-5

Licostinel

Description:

Licostinel, with the CAS number 153504-81-5, is a chemical compound that has been studied primarily for its potential therapeutic applications. It is classified as a selective antagonist of the N-methyl-D-aspartate (NMDA) receptor, which plays a crucial role in synaptic plasticity and memory function. The compound exhibits neuroprotective properties, making it of interest in the context of neurodegenerative diseases and conditions associated with excitotoxicity. Licostinel has been investigated for its efficacy in various preclinical and clinical settings, particularly in relation to stroke and traumatic brain injury. Its mechanism of action involves modulating glutamate activity, thereby reducing neuronal damage. Additionally, Licostinel's pharmacokinetic profile, including absorption, distribution, metabolism, and excretion, is essential for understanding its therapeutic potential and safety. As research continues, further insights into its efficacy and safety profile will help determine its role in clinical applications.

Formula: C₈H₃Cl₂N₃O₄

InChI: InChI=1S/C8H3Cl2N3O4/c9-2-1-3-5(6(4(2)10)13(16)17)12-8(15)7(14)11-3/h1H,(H,11,14)(H,12,15)

InChI key: InChIKey=CHFSOFHQIZKQCR-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C2C(=CC(Cl)=C1Cl)NC(=O)C(=O)N2

Synonyms:

• 2,3-Quinoxalinedione, 6,7-dichloro-1,4-dihydro-5-nitro-
• 5-Nitro-6,7-dichloro-1,4-dihydro-2,3-quinoxalinedione
• 5-Nitro-6,7-dichloro-2,3-quinoxalinedione
• 6,7-Dichloro-1,4-dihydro-5-nitro-2,3-quinoxalinedione
• 6,7-Dichloro-1,4-dihydro-5-nitroquinoxalin-2,3-dione
• 6,7-Dichloro-5-Nitro-1,4-Dihydroquinoxaline-2,3-Dione
• 6,7-Dichloro-5-nitro-2,3-quinoxalinedione
• Acea 1021
• Licostinel [USAN]
• Unii-3Z3037Ljtc
• Licostinel

6,​7-​Dichloro-​1,​4-​dihydro-​5-​nitro-​2,​3-​quinoxalinedione

CAS: 153504-81-5

Formula: C₈H₃Cl₂N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 276.0331

Ref: IN-DA00B8LM

Licostinel

CAS: 153504-81-5

Licostinel

Purity: ≥95%

Molecular weight: 276.03g/mol

Ref: 54-BUP06412

6,7-DICHLORO-5-NITROQUINOXALINE-2,3(1H,4H)-DIONE

CAS: 153504-81-5

Formula: C₈H₃Cl₂N₃O₄

Purity: 95%

Molecular weight: 276.03

Ref: 10-F531276

Licostinel

CAS: 153504-81-5

Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.

Formula: C₈H₃Cl₂N₃O₄

Purity: 98.02%

Color and Shape: Solid

Molecular weight: 276.03

Ref: TM-T27828