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CAS 153645-26-2

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(S)-(-)-N-Boc-tert-leucinol

Description:
(S)-(-)-N-Boc-tert-leucinol is a chiral amino alcohol that is commonly used in organic synthesis, particularly in the preparation of pharmaceuticals and biologically active compounds. The "N-Boc" designation indicates that the amine group is protected by a tert-butyloxycarbonyl (Boc) group, which is a common protecting group in peptide synthesis. The "tert-leucinol" part refers to the presence of a tert-leucine moiety, which contributes to its stereochemistry and biological activity. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and methanol. Its chirality is significant for applications in asymmetric synthesis, where the specific configuration can influence the biological properties of the resulting compounds. Additionally, (S)-(-)-N-Boc-tert-leucinol can be utilized in the synthesis of various derivatives and can serve as a building block in the development of more complex molecules. Proper handling and storage conditions are essential due to its potential reactivity and the need to maintain its chiral integrity.
Formula:C11H23NO3
InChI:InChI=1/C11H23NO3/c1-10(2,3)8(7-13)12-9(14)15-11(4,5)6/h8,13H,7H2,1-6H3,(H,12,14)/t8-/m1/s1
SMILES:CC(C)(C)[C@@H](CO)N=C(O)OC(C)(C)C
Synonyms:
  • tert-butyl [(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]carbamate
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