CAS 153666-19-4

ketodeoxynonulosonic acid

Description:

Ketodeoxynonulosonic acid (KDN) is a naturally occurring sugar acid that belongs to the family of sialic acids, which are nine-carbon sugars typically found in animal tissues. KDN is characterized by its keto group at the second carbon and a deoxy group at the third carbon, distinguishing it from other sialic acids like neuraminic acid. This compound plays a significant role in biological processes, particularly in cell recognition and signaling, as it is often found on the surface of glycoproteins and glycolipids. KDN is known for its involvement in immune responses and cellular interactions, contributing to the modulation of various physiological functions. Its unique structure allows it to participate in various biochemical pathways, making it a subject of interest in research related to glycobiology and immunology. Additionally, KDN's presence in certain bacterial species highlights its potential implications in microbiology and infectious diseases. Overall, ketodeoxynonulosonic acid is a vital component in the study of cellular interactions and biological functions.

Formula: C₉H₁₆O₉

InChI: InChI=1/C9H16O9/c10-2-4(12)6(14)7-5(13)3(11)1-9(17,18-7)8(15)16/h3-7,10-14,17H,1-2H2,(H,15,16)/p-1/t3-,4+,5+,6-,7-,9-/m0/s1

Synonyms:

• Ketodeoxynonulosonic acid (Kdn)
• (2S,4S,5R,6R)-2,4,5-trihydroxy-6-[(1S,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• (2S,4S,5R,6S)-2,4,5-trihydroxy-6-[(1S,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• Ketodeoxynonulosonic acidfree acid (Kdn)
• D-glycero-D-galacto-2-Nonulopyranosonic acid, 3-deoxy-

KETODEOXYNONULOSONIC ACID

CAS: 153666-19-4

Formula: C₉H₁₆O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 268.2179

Ref: IN-DA00AQDE

(4S,5R,6R)-2,4,5-Trihydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

CAS: 153666-19-4

(4S,5R,6R)-2,4,5-Trihydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Purity: 98%

Molecular weight: 268.22g/mol

Ref: 54-OR1063654

3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid

CAS: 153666-19-4

Sialic acid derivative crucial for cell function and involved in cancer; found in trout egg glycoproteins and aids in studying polysialoglycoproteins.

Formula: C₉H₁₆O₉

Color and Shape: Solid

Molecular weight: 268.22

Ref: TM-T36117

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid

CAS: 153666-19-4

Formula: C₉H₁₆O₉

Molecular weight: 268.22

Ref: 7W-GC2698

3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid

Controlled Product

CAS: 153666-19-4

Stability Hygroscopic
Applications A naturally occuring deaminated sialic acid, exclusively located at the non-reducing end of the sialyl chains. KDN is a sialic acid derivative with potential for anticancer activity. KDN has also been seen to be in elevated levels in human prostate cancer cells.
References Nadano, D., et al.: J. Biol. Chem., 261, 11550 (1986); Tiralongo, J. et al.: Carb. Mod. Biocatal., 477 (2012); Yabu, M. et al.: Glycobiol., 23, 634 (2013);

Formula: C₉H₁₆O₉

Color and Shape: Neat

Molecular weight: 268.22

Ref: TR-D239500

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid

CAS: 153666-19-4

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (3DG) is a monosaccharide that is present in many biological molecules, such as glycoproteins and glycoconjugates. 3DG is found in the sialic acid residues of glycoproteins and has been shown to have anticancer properties through its ability to inhibit cell growth. This compound also inhibits the synthesis of DNA and RNA by binding to bacterial 16S ribosomal RNA, inhibiting protein synthesis and cell division. 3DG has been used in biocompatible polymers for medical applications, such as drug delivery systems.

Formula: C₉H₁₆O₉

Purity: Min. 98 Area-%

Color and Shape: White Yellow Powder

Molecular weight: 268.22 g/mol

Ref: 3D-MD04703