CAS 153707-88-1

1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazol-3,5-dione

Description:

1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazol-3,5-dione, with CAS number 153707-88-1, is a synthetic chemical compound characterized by its complex molecular structure, which includes a triazole ring, a piperazine moiety, and phenoxyethyl groups. This compound exhibits potential pharmacological properties, particularly in the realm of neuropharmacology, due to the presence of the piperazine ring, which is often associated with various biological activities, including anxiolytic and antidepressant effects. The chlorophenyl group may contribute to its lipophilicity, influencing its ability to cross biological membranes. The triazole component is known for its role in antifungal and antimicrobial activities, suggesting that this compound may also possess similar properties. Its solubility, stability, and reactivity can vary depending on environmental conditions, making it important for researchers to consider these factors in experimental applications. Overall, this compound represents a class of molecules that may have significant therapeutic potential, warranting further investigation into its biological effects and mechanisms of action.

Formula: C₂₃H₂₈ClN₅O₃

InChI: InChI=1S/C23H28ClN5O3/c24-19-6-4-7-20(18-19)27-14-12-26(13-15-27)10-5-11-29-23(31)28(22(30)25-29)16-17-32-21-8-2-1-3-9-21/h1-4,6-9,18H,5,10-17H2,(H,25,30)

InChI key: InChIKey=BTNXVMLCKOPOEP-UHFFFAOYSA-N

SMILES: ClC=1C=C(C=CC1)N2CCN(CCCN3C(=O)N(CCOC4=CC=CC=C4)C(=O)N3)CC2

Synonyms:

• 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazolidine-3,5-dione
• BMS 180492
• 1,2,4-Triazolidine-3,5-dione, 1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-
• 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazol-3,5-dione
• Triazoledione (td)
• UNII-3508097W2U
• Nefazodone 3,5-Dione

1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazolidine-3,5-dione

Controlled Product

CAS: 153707-88-1

Applications 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4-(2-phenoxyethyl)-1,2,4-triazolidine-3,5-dione, is a metabolite of Nefazodone (N389100), that has been shown to act as antidepressants that inhibit the serotonin (SERT) and norepinephrine transporters (NET).
References Eison, A.S., et al.: Psychopharmacol. Bull., 26, 311 (1990), Keller, M.B., et al.: N. Engl. J. Med., 342, 1462 (2000); Owens, M., et al.: J. Pharmacol. Exp. Therap., 283, 1305 (1997);

Formula: C₂₃H₂₈ClN₅O₃

Color and Shape: Neat

Molecular weight: 457.95

Ref: TR-C380365

BMS-180492

CAS: 153707-88-1

BMS-180492 is a bio-active chemical.

Formula: C₂₃H₂₈ClN₅O₃

Color and Shape: Solid

Molecular weight: 457.95

Ref: TM-T30496