CAS 153773-82-1

Ertapenem sodium

Description:

Ertapenem sodium is a broad-spectrum, injectable antibiotic belonging to the carbapenem class of beta-lactam antibiotics. It is primarily used to treat a variety of bacterial infections, including those caused by Gram-positive and Gram-negative bacteria, as well as anaerobes. Ertapenem exhibits a high degree of stability against many beta-lactamases, making it effective against resistant strains. The compound is characterized by its ability to penetrate bacterial cell walls effectively, leading to the inhibition of cell wall synthesis, which is crucial for bacterial growth and survival. It is typically administered via intravenous or intramuscular routes and has a relatively long half-life, allowing for once-daily dosing. Ertapenem is not effective against certain organisms, such as Pseudomonas aeruginosa and Acinetobacter species. Common side effects may include gastrointestinal disturbances, headache, and potential allergic reactions. As with all antibiotics, appropriate susceptibility testing is recommended to ensure its efficacy against specific pathogens.

Formula: C₂₂H₂₅N₃O₇S·Na

InChI: InChI=1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/t9-,10-,13+,14+,15-,16-;/m1./s1

InChI key: InChIKey=OBWHPSQEAHSXMM-HRXMHBOMSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1S[C@H]3C[C@@H](C(NC4=CC(C(O)=O)=CC=C4)=O)NC3)[H].[Na]

Synonyms:

• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, sodium salt (1:1), (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, monosodium salt, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-
• Ertapenem Sodium
• Ertapenem monosodium
• Invanz
• L 749345
• Mk 826
• sodium 3-{[(4S)-4-({(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl}sulfanyl)-L-prolyl]amino}benzoate

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid,3-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)-

CAS: 153773-82-1

Formula: C₂₂H₂₄N₃NaO₇S

Purity: 97%

Color and Shape: Solid

Molecular weight: 497.4966

Ref: IN-DA01CC83

Ertapenem Sodium Salt

CAS: 153773-82-1

Formula: C₂₂H₂₄N₃O₇S·Na

Molecular weight: 474.51 22.99

Ref: 4Z-E-071018

Ertapenem sodium

CAS: 153773-82-1

Ertapenem sodium

Purity: ≥95%

Molecular weight: 497.5g/mol

Ref: 54-BUP15434

Ertapenem sodium salt

CAS: 153773-82-1

Formula: C₂₂H₂₄N₃NaO₇S

Purity: ≥ 90.0% (dried basis)

Color and Shape: White to off-white powder

Molecular weight: 497.5

Ref: 7W-GA8176

Ertapenem sodium

CAS: 153773-82-1

Ertapenem sodium (MK-826) is a long-acting carbapenem antibiotic effective against a wide range of bacteria, including ESBL producers.

Formula: C₂₂H₂₄N₃O₇S·Na

Purity: 96.05% - 99.92%

Color and Shape: White Or Off-White Powder

Molecular weight: 497.5

Ref: TM-T4991

Ertapenem sodium

CAS: 153773-82-1

Ertapenem sodium is a carbapenem antibiotic with action on bacterial cell wall synthesis and is used for treating severe bacterial infections like intra-abdominal infections and pneumonia.

Formula: C₂₂H₂₄N₃NaO₇S

Purity: Min. 85 Area-%

Color and Shape: Powder

Molecular weight: 497.5 g/mol

Ref: 3D-AE35185