CAS 1538-09-6

Benzathine penicillin

Description:

Benzathine penicillin is a long-acting form of penicillin, primarily used as an antibiotic to treat various bacterial infections, particularly rheumatic fever and syphilis. It is a salt of penicillin G, characterized by its extended duration of action due to its slow release from the injection site. The compound is typically administered via intramuscular injection and is known for its effectiveness against a range of gram-positive bacteria. Benzathine penicillin is relatively stable in solution and has a low solubility in water, which contributes to its prolonged therapeutic effects. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Common side effects may include allergic reactions, pain at the injection site, and gastrointestinal disturbances. Due to its pharmacokinetic properties, benzathine penicillin is often used in prophylactic treatments to prevent infections in high-risk populations. Overall, it remains a vital component in the management of certain infectious diseases, particularly in settings where adherence to daily medication regimens may be challenging.

Formula: C₁₆H₂₀N₂·2C₁₆H₁₈N₂O₄S

InChI: InChI=1S/C16H18N2O4S.C16H20N2/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,17-18H,11-14H2/t11-,12+,14-;/m1./s1

InChI key: InChIKey=JTFXYBGKLCCFSP-LQDWTQKMSA-N

SMILES: C(NCCNCC1=CC=CC=C1)C2=CC=CC=C2.C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(CC3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H]

Synonyms:

• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine (2:1)
• 1,2-Ethanediamine, N,N′-bis(phenylmethyl)-, bis[(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• 1,2-Ethanediamine, N,N′-bis(phenylmethyl)-, bis[[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-, compd. with N,N′-dibenzylethylenediamine (2:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]- (2S,5R,6R)-, compd. with N¹,N²-bis(phenylmethyl)-1,2-ethanediamine (2:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, compd. with N,N′-bis(phenylmethyl)-1,2-ethanediamine (2:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- [2S-(2α,5α,6β)]-, compd. with N,N′-bis(phenylmethyl)-1,2-ethanediamine (2:1)
• Beacillin
• Benepen
• Benzacillin
• Benzapen
• Benzathine Benzylpenicillin
• Benzathine Penicillin
• Benzathine penicillin G
• Benzethacil
• Benzylpenicillin N,N′-dibenzylethylenediamine salt
• Benzylpenicillin benzathine
• Benzylpenicillin dibenzylethylenediamine salt
• Bica-penicillin
• Bicillin
• Bicillin 1
• Bicillin G
• Bicillin I
• Bicillin L-A
• Cepacilina
• Cillenta
• Debecillin
• Debecylina
• Diamine penicillin
• Dibencil
• Dibencillin
• Dibenzylethylenediamine dipenicillin G
• Duropenin
• Ethylenediamine, N,N′-dibenzyl-, bis[3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• Ethylenediamine, N,N′-dibenzyl-, compd. with penicillin G (1:2)
• Extencilline
• Extenicilline
• Lentopenil
• Longacilina
• Longicil
• Megacillin suspension
• Moldamin
• N,N-dibenzylethylenediammonium bis(6-benzylpenicillanate)
• N,N′-Dibenzylethylenediamine bis[benzyl penicillin]
• N,N′-Dibenzylethylenediamine salt of benzylpenicillin
• Neolin
• Pen-Di-Ben
• Penadur
• Pendepon
• Penditan
• Penduran
• Penicillin G Benzathin
• Penicillin G, N,N′-dibenzylethylenediamine salt
• Penicillin G, compd. with N,N′-dibenzylethylenediamine (2:1)
• Penicom 12
• Penidural
• Penidure
• Permapen
• Strepdipen-Suspension
• Tardocillin
• Vicin

BENZATHINE BENZYLPENICILLIN CRS

CAS: 1538-09-6

BENZATHINE BENZYLPENICILLIN CRS

Formula: C₄₈H₅₆N₆O₈S₂

Color and Shape: White. Powder.

Molecular weight: 909.1236

Ref: 41-B0500000

Penicillin G benzathine

CAS: 1538-09-6

Penicillin G benzathine

Molecular weight: 909.13g/mol

Ref: 54-BUP13973

Penicillin G benzathine

CAS: 1538-09-6

Penicillin G benzathine has anti-bacterial infectious activity and can be used to study early syphilis.

Formula: C₄₈H₅₆N₆O₈S₂

Purity: 97.99%

Color and Shape: Coa

Molecular weight: 909.13

Ref: TM-T16465

Penicillin G benzathine

CAS: 1538-09-6

Formula: C₄₈H₅₆N₆O₈S₂

Purity: ≥ 98.0%

Color and Shape: White to faint yellow or faint beige powder or crystals

Molecular weight: 909.12

Ref: 7W-GA7804

Benzylpenicillin Benzathine

Controlled Product

CAS: 1538-09-6

Formula: C₁₆H₂₀N₂C₁₆H₁₈N₂O₄S

Color and Shape: Neat

Molecular weight: 909.12

Ref: 86-MM0513.00

Benzathine penicilline G

Controlled Product

CAS: 1538-09-6

Formula: C₁₆H₂₀N₂C₁₆H₁₈N₂O₄S

Color and Shape: Neat

Molecular weight: 909.12

Ref: 04-C10532490

Penicillin G benzathine anhydrous

CAS: 1538-09-6

Penicillin G benzathine anhydrous is a penicillin antibiotic. It is used to treat bacterial infections, including syphilis, streptococcal pharyngitis, and other infectious diseases. Penicillin G benzathine anhydrous is administered intramuscularly or intravenously. The drug can be detected in the blood after administration, which makes it useful for diagnosis of infectious diseases. Penicillin G benzathine anhydrous has shown statistically significant efficacy in treatment trials that were conducted on patients with infectious diseases. However, there have been increasing reports of high resistance to this drug in recent years. Interferon alfa-2b may be used as adjunctive therapy for resistant cases.

Formula: C₁₆H₂₀N₂•(C₁₆H₁₈N₂O₄S)₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 909.13 g/mol

Ref: 3D-FP32157

Benzylpenicillin Benzathine

CAS: 1538-09-6

Color and Shape: Neat

Ref: 61-FOR0513.00