CAS 1538-75-6

Trimethylacetic anhydride

Description:

Trimethylacetic anhydride, with the CAS number 1538-75-6, is an organic compound characterized by its anhydride functional group derived from trimethylacetic acid. It is a colorless to pale yellow liquid with a distinctive odor. This compound is known for its reactivity, particularly in acylation reactions, where it can introduce the trimethylacetyl group into various substrates. It has a relatively low boiling point and is soluble in organic solvents, making it useful in organic synthesis. Trimethylacetic anhydride is often employed in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Due to its anhydride nature, it can react with water to form trimethylacetic acid, releasing heat in the process. Safety precautions are necessary when handling this substance, as it can be irritating to the skin and eyes, and its vapors may be harmful if inhaled. Proper storage in a cool, dry place away from moisture is essential to maintain its stability and reactivity.

Formula: C₁₀H₁₈O₃

InChI: InChI=1/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3

InChI key: InChIKey=PGZVFRAEAAXREB-UHFFFAOYSA-N

SMILES: O(C(C(C)(C)C)=O)C(C(C)(C)C)=O

Synonyms:

• 2,2,2-Trimethylacetic anhydride
• 2,2-Dimethylpropanoic Anhydride
• 2,2-Dimethylpropanoic acid anhydride
• 2,2-Dimethylpropanoyl 2,2-dimethylpropanoate
• 2,2-Dimethylpropanoyl anhydride
• 2,2-Dimethylpropionic anhydride
• Neopentanoic anhydride
• Pivalic acid anhydride
• Pivalic anhydride
• Pivaloyl anhydride
• Propanoic acid, 2,2-dimethyl-, 1,1′-anhydride
• Propanoic acid, 2,2-dimethyl-, anhydride
• Trimethylacetic acid anhydride
• Propanoicacid,2,2-dimethyl-,anhydride
• Pivalic anydride
• TRIMETHYLACETIC ANHYDRIDE
• Dipivalic anhydride
• BIS(TRIMETHYLACETIC) ANHYDRIDE
• Bis(2,2-dimethylpropionic acid)anhydride
• 2,2-DIMETHYLPROPIONIC ACID ANHYDRIDE
• Bis(2,2-dimethylpropionic)anhydride
• Bis(pivalic acid)anhydride
• 1,1-Dimethylpropanoic anhydride
• 2,2-Dimethylpropanoicanhydride
• Bis(pivalic)anhydride
• 2,2-Dimethylpropionic anhydride, Pivalic anhydride

Trimethylacetic anhydride, 99%

CAS: 1538-75-6

Trimethylacetic anhydride is used as acylation and esterification reagents. It is involved in acylation and esterification reactions with anilines and phenols. It is also used in solid-phase oligonucleotide synthesis and in the kinetic resolution of racemic 2-hydroxy-gamma-butyrolactones with diphen

Formula: C₁₀H₁₈O₃

Purity: 99%

Color and Shape: Clear colorless, Liquid

Molecular weight: 186.25

Ref: 02-B22983

Trimethylacetic anhydride

CAS: 1538-75-6

Formula: C₁₀H₁₈O₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 186.2481

Ref: IN-DA0035HW

Trimethylacetic anhydride

CAS: 1538-75-6

Trimethylacetic anhydride

Purity: ≥95%

Molecular weight: 186.25g/mol

Ref: 54-BUP16041

Trimethylacetic anhydride

CAS: 1538-75-6

Formula: C₁₀H₁₈O₃

Molecular weight: 186.25

Ref: 7W-GK7182

Pivalic Anhydride

CAS: 1538-75-6

Formula: C₁₀H₁₈O₃

Purity: >98.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 186.25

Ref: 3B-P1414

Pivalic anhydride

CAS: 1538-75-6

Formula: C₁₀H₁₈O₃

Purity: 98.0%

Color and Shape: Liquid, Clear

Molecular weight: 186.251

Ref: 10-F241268

Adefovir Dipivoxil Impurity 15 (Pivalic Anhydride)

CAS: 1538-75-6

Formula: C₁₀H₁₈O₃

Molecular weight: 186.25

Ref: 4Z-A-3625

Trimethylacetic anhydride

CAS: 1538-75-6

Trimethylacetic anhydride (Pivalic anhydride) is used as medical intermediate

Formula: C₁₀H₁₈O₃

Purity: ≥95%

Color and Shape: Clear Colourless Liquid

Molecular weight: 186.25

Ref: TM-T0546

Trimethylacetic anhydride

CAS: 1538-75-6

Trimethylacetic anhydride

Formula: C₁₀H₁₈O₃

Purity: 98+%

Color and Shape: clear. colourless liquid

Molecular weight: 186.25g/mol

Ref: 54-OR323269

Trimethylacetic Anhydride

Controlled Product

CAS: 1538-75-6

Applications A metabolite of a double prodrug (6-dGCV-DPiv) of Ganciclovir (G235000).
References Krasny, H.C., et al.: Drug Metab. Dispos., 23, 1242 (1995),

Formula: C₁₀H₁₈O₃

Color and Shape: Neat

Molecular weight: 186.25

Ref: TR-T795760

Adefovir Dipivoxil Impurity 15

CAS: 1538-75-6

Formula: C₁₀H₁₈O₃

Molecular weight: 186.25

Ref: ST-EA-CP-A172010