CAS 153804-05-8

Pratosartan

Description:

Pratosartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby lowering blood pressure. The chemical structure of Pratosartan features a biphenyl group and a carboxylic acid moiety, contributing to its pharmacological activity. It is characterized by its high selectivity for the angiotensin II receptor subtype 1 (AT1), which is crucial for its therapeutic effects. Pratosartan is typically administered orally and exhibits a favorable pharmacokinetic profile, including good bioavailability and a moderate half-life, allowing for once-daily dosing. Additionally, it is generally well-tolerated, with a side effect profile similar to other medications in its class, including dizziness, fatigue, and potential renal effects. As with all antihypertensives, monitoring of blood pressure and renal function is recommended during treatment.

Formula: C₂₅H₂₆N₆O

InChI: InChI=1S/C25H26N6O/c1-2-7-23-26-21-10-5-6-11-22(32)24(21)31(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)25-27-29-30-28-25/h3-4,8-9,12-15H,2,5-7,10-11,16H2,1H3,(H,27,28,29,30)

InChI key: InChIKey=KCTFTBCZZUBAKN-UHFFFAOYSA-N

SMILES: C(N1C2=C(N=C1CCC)CCCCC2=O)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5

Synonyms:

• 153804-05-8
• 4(3H)-Cycloheptimidazolone, 5,6,7,8-tetrahydro-2-propyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• 4(3H)-Cycloheptimidazolone, 5,6,7,8-tetrahydro-2-propyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• 5,6,7,8-Tetrahydro-2-propyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-4(3H)-cycloheptimidazolone
• Fw 7203
• Kd 3-671
• Kt 3-671
• Kt 3671
• Pratosartan
• Pratosartan (JAN)

Pratosartan

CAS: 153804-05-8

Pratosartan is a statin drug used to treat hypercholesterolemia and metabolic disorders. This drug has been shown to reduce the symptoms of these diseases, including muscle pain and weakness, fatigue, headache, and sexual dysfunction. Pratosartan belongs to a class of drugs called HMG-CoA reductase inhibitors that work by blocking the production of cholesterol in the liver. The chemical structure of Pratosartan can be found below.

Formula: C₂₅H₂₆N₆O

Purity: Min. 95%

Molecular weight: 426.5 g/mol

Ref: 3D-DGA80405

Pratosartan

CAS: 153804-05-8

Pratosartan is a selective antagonist of angiotensin II receptor.

Formula: C₂₅H₂₆N₆O

Purity: 98%

Color and Shape: Solid

Molecular weight: 426.51

Ref: TM-T16573