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CAS 153808-85-6

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Cadrofloxacin

Description:
Cadrofloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. The compound features a bicyclic core structure typical of fluoroquinolones, which includes a fluorine atom that enhances its antibacterial potency. Cadrofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. This mechanism disrupts bacterial cell division and growth. The substance is generally administered in oral form and is known for its favorable pharmacokinetic properties, including good absorption and distribution in tissues. However, like other antibiotics, it may have side effects, including gastrointestinal disturbances and potential effects on the central nervous system. Its use is subject to careful consideration to avoid the development of antibiotic resistance. Overall, cadrofloxacin represents an important option in the arsenal of antimicrobial agents, particularly in veterinary medicine.
Formula:C19H20F3N3O4
InChI:InChI=1/C19H20F3N3O4/c1-9-7-24(5-4-23-9)15-13(20)6-11-14(17(15)29-19(21)22)25(10-2-3-10)8-12(16(11)26)18(27)28/h6,8-10,19,23H,2-5,7H2,1H3,(H,27,28)/t9-/m0/s1
SMILES:C[C@H]1CN(CCN1)c1c(cc2c(c1OC(F)F)n(cc(c2=O)C(=O)O)C1CC1)F
Synonyms:
  • Caderofloxacin
  • 1-cyclopropyl-8-(difluoromethoxy)-6-fluoro-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-quinoline-3-carboxylic acid
  • 1-cyclopropyl-8-(difluoromethoxy)-6-fluoro-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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