CAS 154-02-9

5-Hydroxytryptophol

Description:

5-Hydroxytryptophol, also known as 5-HTOL, is a chemical compound derived from the amino acid tryptophan. It is classified as an indole derivative and is structurally related to serotonin, a key neurotransmitter in the central nervous system. This compound is characterized by its hydroxyl group at the 5-position of the indole ring, which contributes to its biological activity. 5-Hydroxytryptophol is known to exhibit psychoactive properties and has been studied for its potential role in modulating sleep and mood. It is also involved in various biochemical pathways, including those related to melatonin synthesis. In terms of solubility, it is generally soluble in water and organic solvents, which facilitates its study in biological systems. The compound has garnered interest in pharmacological research, particularly in understanding its effects on serotonin receptors and its implications in neuropharmacology. Overall, 5-Hydroxytryptophol represents an important substance in the context of neurochemistry and psychopharmacology.

Formula: C₁₀H₁₁NO₂

InChI: InChI=1S/C10H11NO2/c12-4-3-7-6-11-10-2-1-8(13)5-9(7)10/h1-2,5-6,11-13H,3-4H2

InChI key: InChIKey=KQROHCSYOGBQGJ-UHFFFAOYSA-N

SMILES: C(CO)C=1C=2C(NC1)=CC=C(O)C2

Synonyms:

• 1H-Indole-3-ethanol, 5-hydroxy-
• 3-(2-hydroxyethyl)-1H-indol-5-ol
• 5-Hydroxy-1H-indole-3-ethanol
• 5-Hydroxy-3-(2-hydroxyethyl)indole
• 5-Hydroxyindole-3-(2-hydroxy)ethyl
• 5-Hydroxytryptophol
• Indole-3-ethanol, 5-hydroxy-
• NSC 84416
• Tryptophol, 5-hydroxy-

5-Hydroxytryptophol

CAS: 154-02-9

Formula: C₁₀H₁₁NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 177.1998

Ref: IN-DA00APG9

5-Hydroxytryptophol

CAS: 154-02-9

5-Hydroxytryptophol

Purity: 100.0% (gc) (Typical Value in Batch COA)

Color and Shape: off-white crystalline powder

Molecular weight: 177.20g/mol

Ref: 54-BIB6072

5-Hydroxy Tryptophol

CAS: 154-02-9

Formula: C₁₀H₁₁NO₂

Molecular weight: 177.20

Ref: 4Z-T-220004

5-Hydroxytryptophol

CAS: 154-02-9

5-Hydroxytryptophol is a metabolite of tryptophan. It is used as a biomarker for recent alcohol consumption and causes sleeping sickness

Formula: C₁₀H₁₁NO₂

Purity: 95.49%

Color and Shape: Solid

Molecular weight: 177.2

Ref: TM-T7641

5-Hydroxy Tryptophol

Controlled Product

CAS: 154-02-9

Applications A metabolite of Tryptophan (T947200).
References da Prada, M., et al.: Biochem. Pharmacol., 14, 1721 (1965), Curzon, G., et al.: Br. J. Pharmacol., 63, 627 (1978), Fukumori, R., et al.: J. Pharm. Pharmacol., 33, 586 (1981), Aasmoe, L., et al.: Biochem. Pharmacol., 57, 1067 (1999), Karamanakos, P., et al.: Pharmacol. Toxicol., 88, 106 (2001),

Formula: C₁₀H₁₁NO₂

Color and Shape: Neat

Molecular weight: 177.20

Ref: TR-H976000

5-Hydroxytryptophol

CAS: 154-02-9

5-Hydroxytryptophol is a fine chemical that can be used as a versatile building block, useful intermediate, or reaction component. It is a speciality chemical with high purity and quality. 5-Hydroxytryptophol has been shown to react with benzaldehyde in the presence of sodium hydroxide to form a complex compound. This product has been used as a research chemical, which can be used to make other chemicals such as serotonin and melatonin.

Formula: C₁₀H₁₁NO₂

Purity: Min. 99.0 Area-%

Molecular weight: 177.20 g/mol

Ref: 3D-H-8500

5-Hydroxy tryptophol

CAS: 154-02-9

5-Hydroxy tryptophol is a quinone derivative that has been used as a pharmacological treatment for the carcinoid syndrome. It inhibits the conversion of 5-hydroxytryptophol to serotonin, and it can be used in the diagnosis of carcinoid syndrome. 5-HTP is also an important precursor of serotonin in vivo and its concentrations are increased in the skin cells of patients with carcinoid syndrome. Chronic exposure to ethanol or other drugs may cause excessive production of serotonin, which leads to symptoms such as anxiety, nausea, diarrhea, flushing, headache, and insomnia. As a result of this chronic exposure, 5-HTP concentrations are increased in skin cells because it is an important precursor for serotonin synthesis. 5-HTP concentrations are also increased in erythrocytes and platelets due to chronic exposure to ethanol or other drugs. Finally, chronic exposure to ethanol or other drugs causes oxidative stress by increasing reactive oxygen species production. This causes changes in enzyme

Formula: C₁₀H₁₁NO₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 177.2 g/mol

Ref: 3D-FH24155

5-Hydroxytryptophol

CAS: 154-02-9

Formula: C₁₀H₁₁NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 177.203

Ref: 10-F233489