CAS 154-08-5

5-Fluoro-DL-tryptophan

Description:

5-Fluoro-DL-tryptophan is an amino acid derivative characterized by the presence of a fluorine atom at the 5-position of the indole ring of tryptophan. It is a non-proteinogenic amino acid, meaning it is not incorporated into proteins during translation. This compound is often used in biochemical research, particularly in studies involving protein structure and function, as it can serve as a fluorescent probe or a tool for studying enzyme mechanisms. The presence of the fluorine atom can influence the electronic properties and reactivity of the molecule, potentially affecting its interactions with biological macromolecules. 5-Fluoro-DL-tryptophan is typically synthesized through chemical methods and may exhibit different solubility characteristics compared to its non-fluorinated counterpart. As with many fluorinated compounds, it may also display unique pharmacological properties, making it of interest in medicinal chemistry. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity and environmental impact.

Formula: C₁₁H₁₁FN₂O₂

InChI: InChI=1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)

InChI key: InChIKey=INPQIVHQSQUEAJ-UHFFFAOYSA-N

SMILES: C(C(C(O)=O)N)C=1C=2C(NC1)=CC=C(F)C2

Synonyms:

• Tryptophan, 5-fluoro-, DL-
• Tryptophan, 5-fluoro-
• DL-Tryptophan, 5-fluoro-
• 5-Fluorotryptophan
• 5-Fluoro-DL-tryptophan

2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid

CAS: 154-08-5

Formula: C₁₁H₁₁FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 222.2156

Ref: IN-DA003MRM

5-Fluoro-DL-tryptophan

CAS: 154-08-5

Molecular weight: 222.22

Ref: 7W-GM0076

5-Fluoro-DL-tryptophan

CAS: 154-08-5

5-Fluoro-DL-tryptophan

Formula: C₁₁H₁₁FN₂O₂

Purity: 99%

Color and Shape: off white solid

Molecular weight: 222.22g/mol

Ref: 54-PC4377Z

5-Fluoro D,L-tryptophan

CAS: 154-08-5

5-Fluoro D,L-tryptophan (5FDTL) is a tryptophan analog that inhibits the growth of bacteria by binding to fatty acid synthesis enzymes. 5FDTL binds to wild-type and resistant mutants of bacterial fatty acid synthases, which are proteins that catalyze the formation of long-chain fatty acids from acetyl-CoA. This binding prevents the formation of long-chain fatty acids, which are required for bacterial cell replication. 5FDTL also binds to protein data and has been shown to have an anti-infective effect on wild-type strains of Pseudomonas aeruginosa and Escherichia coli as well as Pichia pastoris. Disulfide bonds in 5FDTL stabilize its secondary structure and provide protection against proteolytic degradation by enzymes in the extracellular environment. The structural analysis of 5FDTL has revealed that it consists of a small molecule with a logarithmic growth phase

Formula: C₁₁H₁₁FN₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 222.22 g/mol

Ref: 3D-FF23354

5-Fluoro-DL-tryptophan

CAS: 154-08-5

Formula: C₁₁H₁₁FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 222.219

Ref: 10-F009449

5-Fluoro D,L-Tryptophan Hydrochloride

Controlled Product

CAS: 154-08-5

Applications A metabolic antagonist of tryptophan.

Formula: C₁₁H₁₁FN₂O₂

Color and Shape: Neat

Molecular weight: 222.22

Ref: TR-F595700