CAS 154-17-6

2-Deoxyglucose

Description:

2-Deoxyglucose (2-DG) is a glucose analog that is structurally similar to glucose but lacks one oxygen atom at the second carbon position. Its chemical formula is C6H12O5, and it is classified as a monosaccharide. 2-Deoxyglucose is a white crystalline powder that is soluble in water, making it suitable for various biochemical applications. It is primarily known for its role in research, particularly in cancer metabolism and as a potential therapeutic agent, as it can inhibit glycolysis by competing with glucose for uptake and phosphorylation. This property makes it of interest in studies related to tumor growth and energy metabolism. Additionally, 2-DG has been investigated for its potential use in antiviral therapies, including those targeting viral infections. However, its use in clinical settings is still under investigation, and it is not widely approved for therapeutic use. Safety and handling precautions are necessary, as with any chemical substance, to mitigate potential risks associated with exposure.

Formula: C₆H₁₂O₅

InChI: InChI=1/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2/t3-,4-,5-,6+/m1/s1

InChI key: InChIKey=VRYALKFFQXWPIH-PBXRRBTRSA-N

SMILES: [C@H]([C@@H](CC=O)O)([C@@H](CO)O)O

Synonyms:

• 2-Deoxy-<span class="text-smallcaps">D</span>-arabino-hexose
• 2-Deoxy-<span class="text-smallcaps">D</span>-glucose
• 2-Deoxy-<span class="text-smallcaps">D</span>-mannose
• 2-Deoxy-D-Arabino
• 2-Deoxy-D-mannose
• 2-Deoxyglucose
• 2-Deoxyhexopyranose
• 2-Desoxy-<span class="text-smallcaps">D</span>-glucose
• 2-Desoxy-D-glucose
• 2-deoxy-D-arabino-hexopyranose
• 2-deoxy-D-arabino-hexose
• 2-deoxy-D-glucose grade ii
• 2-deoxy-D-glucose grade iii
• 2-deoxy-D-glucose sigmaultra
• 2-deoxy-D-glucose, mixture of anomers
• 2-deoxy-alpha-D-arabino-hexopyranose
• 2-deoxy-beta-D-arabino-hexopyranose
• 2-desoxi-D-glucosa
• <span class="text-smallcaps">D</span>-Glucose, 2-deoxy-
• <span class="text-smallcaps">D</span>-arabino-Hexose, 2-deoxy-
• Ba 2758
• D-Glucose, 2-deoxy-
• D-arabino-Hexose, 2-deoxy-
• Deoxy-d-glucose
• Nsc 15193
• 2-deoxy-glucos
• 2-deoxy-d-arabino-hexos
• 2-DEOXY-D-GLUCOSE
• ba2758
• deoxyglucose
• 2-DEOXY-D-ARABINOHEXOSE
• D-Arabino-2-deoxyhexose
• 2-dg
• nsc15193
• d-2-deoxyglucose
• D-2-GLUCODESOSE
• DEOXY-D-GLUCOSE,2-

2-Deoxy-D-glucose

CAS: 154-17-6

Formula: C₆H₁₂O₅

Purity: >97.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 164.16

Ref: 3B-D0051

2-Deoxy-D-glucose, 98%

CAS: 154-17-6

2-Deoxy-D-glucose is act as a culture media part in molecular genetics and as a targeted optical imaging agent for fluorescent imaging. It finds an application in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). It is utilized in the development of

Formula: C₆H₁₂O₅

Purity: 98%

Color and Shape: White to cream, Powder or crystals or crystalline powder

Molecular weight: 164.16

Ref: 02-L07338

2-Deoxy-D-glucose

CAS: 154-17-6

Formula: C₆H₁₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 164.1565

Ref: IN-DA0038XC

2-Deoxy-D-Glucose-13C6 (Mixture of Isomers)

CAS: 154-17-6

Formula: C₆H₁₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 170.11

Ref: 4Z-G-067025

2-Deoxy-D-glucose

CAS: 154-17-6

2-Deoxy-D-glucose

Formula: C₆H₁₂O₅

Purity: 98%

Color and Shape: off-white to faint brown solid

Molecular weight: 164.15647g/mol

Ref: 54-OR3900T

2-Deoxy-D-glucose

CAS: 154-17-6

2-Deoxy-D-glucose

Purity: ≥95%

Molecular weight: 164.16g/mol

Ref: 54-BUP18508

2-Deoxy-D-glucose

CAS: 154-17-6

Formula: C₆H₁₂O₅

Purity: (GC) ≥ 98.0%

Color and Shape: White to almost white powder

Molecular weight: 164.16

Ref: 7W-GC6248

2-Deoxy-D-glucose

CAS: 154-17-6

2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis.

Formula: C₆H₁₂O₅

Purity: 99.31% - ≥98%

Color and Shape: White Powder

Molecular weight: 164.16

Ref: TM-T6742

2-Deoxy-D-glucose

CAS: 154-17-6

2-Deoxy-D-glucose

Purity: 96%

Molecular weight: 164.15647g/mol

Ref: 54-BICL4266

2-Deoxy-D-glucose-13C6

Controlled Product

CAS: 154-17-6

Applications 2-Deoxy-D-glucose-13C6 is the isotope labelled analogue of 2-Deoxy-D-glucose (D239000), a tumor therapeutic and a targeted optical imaging agent for fluorescent in vivo imaging.
References Knijin, A.. et al.: NMR. BIomed., 13, 124 (2000); Vollers, S.S, et al.: J. BIol. Chem., 287, 42533 (2012); Estan, M.C., et al.: Biochem. Pharmacol., 84, 1604 (2012);

Formula: C₆H₁₂O₅

Color and Shape: White To Off-White

Molecular weight: 170.11

Ref: TR-D239004

2-Deoxy-D-glucose

Controlled Product

CAS: 154-17-6

Applications 2-Deoxy-D-glucose is an inhibitor of glucose metabolism and has been reported to reverse Lupus symptoms in mice in conjunction with metformin (M258815).
References Chem. and Eng. News, page 7, Feb. 23 (2015)

Formula: C₆H₁₂O₅

Color and Shape: White Crystalline

Molecular weight: 164.16

Ref: TR-D239000

2-Deoxy-D-glucose

CAS: 154-17-6

Glycolytic inhibitor; pro-apoptotic; anti-cancer agent

Formula: C₆H₁₂O₅

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 164.16 g/mol

Ref: 3D-MD05187

2-Deoxy-D-glucose

CAS: 154-17-6

Formula: C₆H₁₂O₅

Purity: 98%

Color and Shape: Crystalline

Molecular weight: 164.157

Ref: 10-F024330

2-Deoxy-D-Glucose (2-DG) extrapure AR, 99.9%

CAS: 154-17-6

Formula: C₆H₁₂O₅

Purity: min. 99.9%

Color and Shape: White to off - white, Powder, Clear, Colourless to slight yellow

Molecular weight: 164.16

Ref: SR-43421

2-Deoxy-D-glucose-d8

Controlled Product

CAS: 154-17-6

Formula: C₆D₈H₄O₅

Color and Shape: Neat

Molecular weight: 172.206

Ref: TR-D239006