CAS 154-41-6

Phenylpropanolamine hydrochloride

Description:

Phenylpropanolamine hydrochloride is a sympathomimetic amine that acts as a decongestant and appetite suppressant. It is a white to off-white crystalline powder that is soluble in water and has a slightly bitter taste. The compound is known for its ability to constrict blood vessels, thereby reducing nasal congestion, and it has been used in various over-the-counter medications. Its chemical structure features a phenyl group attached to a propanolamine backbone, which contributes to its pharmacological properties. However, due to safety concerns, particularly regarding its association with increased risk of stroke, the use of phenylpropanolamine in dietary supplements and cold medications has been restricted or banned in several countries. The hydrochloride salt form enhances its stability and solubility, making it suitable for pharmaceutical formulations. As with any medication, it is essential to use phenylpropanolamine hydrochloride under medical supervision to mitigate potential side effects and interactions with other drugs.

Formula:C₉H₁₃NO·ClH

InChI:InChI=1/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9-;/s2

InChI key:InChIKey=DYWNLSQWJMTVGJ-ZSBYJLLINA-N

SMILES:[C@H]([C@@H](C)N)(O)C1=CC=CC=C1.Cl

Synonyms:

(1S,2R)-2-amino-1-phenylpropan-1-ol
(±)-2-Amino-1-phenyl-1-propanol hydrochloride
(±)-Norephedrine chloride
(±)-Norephedrine hydrochloride
(±)-Phenylpropanolamine hydrochloride
2-Amino-1-Phenylpropan-1-Ol Hydrochloride (1:1)
Acutrim
Benzenemethanol, α-(1-aminoethyl)-, hydrochloride, (R*,S*)-
Benzenemethanol, α-[(1R)-1-aminoethyl]-, hydrochloride (1:1), (αS)-rel-
Benzenemethanol, α-[(1R)-1-aminoethyl]-, hydrochloride, (αS)-rel-
DL-2-(2-Chloro Phenyl)Glycine
DL-Phenylpropanolamine hydrochloride
Dexatrim
Flurest
Guaifen
Ip 58064
Kontexin
Monydrin
Mydriatin
NSC 23798
Obestat
Permathene 16
Phenylpropanolamine hcl
Plus-Minus-Phenylpropanolamine*Hydrochloride
Propadrine hydrochloride
Thinz-Span
alpha-(1-Aminoethyl)benzyl alcohol hydrochloride
erythro-Norephedrine hydrochloride
See more synonyms

Purity (%)

100

Found 9 products.

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(1RS,2SR)-Phenylpropanolamine Hydrochloride (D,L-Norephedrine Hydrochloride) 1.0 mg/ml in Methanol (as free base)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
Color and Shape:Single Solution
Ref: 61-AMP0656.00-01
1ml
87.00€
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d,l-Norephedrine.HCl, 1mg/ml in Methanol (as free base)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
Color and Shape:Single Solution
Ref: LP-NOR-662-HC-1LM
1ml
48.00€
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Phenylpropanolamine Hydrochloride(D,L-Norephedrine Hydrochloride)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
Color and Shape:Neat
Ref: 61-FOR0656.00
10mg
338.00€
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(+/-)-Norephedrine-γ,γ,γ-d3 HCl
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
- 345909-04-8
Color and Shape:White To Brown Solid
Ref: 3U-D5820
10mg
523.00€
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50mg
1,447.00€
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Phenylpropanolamine Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
Color and Shape:Neat
Ref: 86-MM0656.00
250mg
1,080.00€
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d,l-Norephedrine.HCl
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
Color and Shape:Neat
Ref: LP-NOR-662-HC-10
10mg
104.00€
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50mg
330.00€
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100mg
744.00€
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PHENYLPROPANOLAMINE HYDROCHLORIDE CRS - * DRUG PRECURSOR
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
PHENYLPROPANOLAMINE HYDROCHLORIDE CRS - * DRUG PRECURSOR
Formula:C₉H₁₄ClNO
Color and Shape:Crystalline Powder. White. Powder.
Molecular weight:187.6666
Ref: 41-P1260000
50mg
115.00€
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Norephedrine hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
Norephedrine hydrochloride is an antimicrobial agent that inhibits the enzyme activities of bacteria. It has been shown to reduce the growth of bacteria that are resistant to other antibiotics, including penicillin and erythromycin. Norephedrine hydrochloride has also been used in combination with other drugs such as phenylpropanolamine and guaifenesin for relief from cold symptoms. This chemical binds to human serum albumin and can be detected by a reaction mechanism that utilizes caproic acid (a fatty acid) as a hydrogen acceptor. Thermodynamic data obtained from the analysis of this drug-enzyme complex indicated favorable binding properties, with a dissociation constant of 3 x 10 M at room temperature. Intramolecular hydrogen bonding interactions may also contribute to its stability.
Formula:C₉H₁₃NO•HCl
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:187.67 g/mol
Ref: 3D-FP61476
100mg
1,294.00€
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250mg
2,102.00€
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Phenylpropanolamine Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 154-41-6
Norephedrine and its salts
Formula:C₉H₁₃NO·ClH
Color and Shape:White Powder
Molecular weight:187.07639
Ref: 45-1534005