CAS 154-68-7

Antazoline phosphate

Description:

Antazoline phosphate is a chemical compound primarily used as an antihistamine in the treatment of allergic conditions. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, potentially leading to sedative effects. The compound is known for its ability to block H1 histamine receptors, thereby alleviating symptoms such as itching, sneezing, and runny nose associated with allergies. Antazoline phosphate is typically presented as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Its chemical structure includes a benzodiazepine ring, contributing to its pharmacological properties. Due to its sedative effects, caution is advised when using this substance, especially in activities requiring alertness. Additionally, it may interact with other medications, necessitating careful consideration in polypharmacy situations. Overall, Antazoline phosphate is an important compound in the field of allergy treatment, with specific characteristics that define its use and efficacy.

Formula: C₁₇H₁₉N₃·H₃O₄P

InChI: InChI=1S/C17H19N3.H3O4P/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);(H3,1,2,3,4)

InChI key: InChIKey=DUIGUKRYYAGJAF-UHFFFAOYSA-N

SMILES: P(=O)(O)(O)O.N(CC1=CC=CC=C1)(CC=2NCCN2)C3=CC=CC=C3

Synonyms:

• 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, phosphate (1:1)
• 2-((N-Benzylanilino)methyl)-2-imidazoline phosphate (1:1)
• 2-Imidazoline, 2-[(N-benzylanilino)methyl]-, phosphate (1:1)
• 2-[(N-Benzylanilino)methyl]-2-imidazoline dihydrogen phosphate
• Antistine phosphate
• N-Benzyl-4,5-dihydro-N-phenyl-1H-imidazole-2-methylamine monophosphate
• N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
• N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline phosphate (1:1)
• Unii-Vpr5Fph326
• Vasocon-A
• Antazoline phosphate

Antazoline Phosphate

CAS: 154-68-7

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Formula: C₁₇H₁₉N₃·H₃O₄P

Color and Shape: White Off-White Powder

Molecular weight: 363.13479

Ref: 45-1038003

Antazoline Phosphate

Controlled Product

CAS: 154-68-7

Formula: C₁₇H₁₉N₃·H₃O₄P

Color and Shape: Neat

Molecular weight: 363.35

Ref: 86-MM0561.00

Antazoline phosphate

CAS: 154-68-7

Antazoline phosphate: H1 histamine receptor antagonist with anticholinergic effects, eases allergies.

Formula: C₁₇H₂₂N₃O₄P

Purity: 98%

Color and Shape: Coa

Molecular weight: 363.35

Ref: TM-T21020

Antazoline Phosphate

Controlled Product

CAS: 154-68-7

Applications Antazoline Phosphate acts as a histamine H1 receptor blocker, functioning as an antihistamine pharmaceutical.
References Constanti, A. et al.: Brit. J. Pharmacol. 58, 583 (1976)

Formula: C₁₇H₁₉N₃·H₃O₄P

Color and Shape: Neat

Molecular weight: 363.35

Ref: TR-A678410

Antazoline Phosphate

CAS: 154-68-7

Color and Shape: Neat

Ref: 61-FOR0561.00