CAS 154-87-0

Thiamine pyrophosphate

Description:

Thiamine pyrophosphate (TPP), also known as thiamine diphosphate, is the active form of vitamin B1 and plays a crucial role as a coenzyme in carbohydrate metabolism. It is characterized by its pyrophosphate group, which is essential for its function in enzymatic reactions, particularly in the decarboxylation of alpha-keto acids and the hexose monophosphate shunt. TPP is a water-soluble compound, which means it readily dissolves in water, facilitating its biological activity in various metabolic pathways. The substance is typically found in the form of a white crystalline powder and is sensitive to heat and light, which can lead to degradation. Its molecular structure includes a thiazole ring and a pyrimidine ring, contributing to its biochemical properties. TPP is vital for the proper functioning of several enzymes, including pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, making it essential for energy production and the synthesis of neurotransmitters. Deficiency in thiamine can lead to serious health issues, such as beriberi and Wernicke-Korsakoff syndrome.

Formula: C₁₂H₁₉N₄O₇P₂S·Cl

InChI: InChI=1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H

InChI key: InChIKey=YXVCLPJQTZXJLH-UHFFFAOYSA-N

SMILES: C([N+]=1C(C)=C(CCOP(OP(=O)(O)O)(=O)O)SC1)C=2C(N)=NC(C)=NC2.[Cl-]

Synonyms:

• 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)thiazolium chloride P,P-dioxide
• B-Neurox
• Berolase
• Biosyth
• Bioxilasi
• Bivitasi
• Co-B1
• Co-B₁
• Cocarbina
• Cocarboxil
• Cocarboxilasa
• Cocarboxylase
• Coenbione
• Coxylase
• Diphosphothiamin
• Diphosphothiamine
• Farmaneurina
• Metabolase
• Nutrase
• Pyrolase
• Pyruvodehydrase
• TDP
• TDP (thiamin ester)
• TPP
• TPP (coenzyme)
• Thiamin pyrophosphate
• Thiamine diphosphate
• Thiamine diphosphate ester chloride
• Thiamine diphosphoric acid ester chloride
• Thiamine pyrophosphate
• Thiamine pyrophosphate chloride
• Thiamine pyrophosphate hydrochloride
• Thiamine pyrophosphoric acid ester chloride
• Thiamine pyrophosphoric ester
• Thiamine, trihydrogen pyrophosphate (ester)
• Thiamine-PP
• Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride, P,P'-dioxide
• Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride (1:1)
• Vitamin B1 pyrophosphate chloride
• 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium chloride
• Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride
• Thiaminium diphosphoric acid ester chloride
• thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-[2-[[hydroxy(phosphonooxy)phosphinyl]oxy]ethyl]-4-methyl-

Thiamine Pyrophosphate Chloride

CAS: 154-87-0

Formula: C₁₂H₁₉ClN₄O₇P₂S

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 460.76

Ref: 3B-T0183

Thiamine pyrophosphate

CAS: 154-87-0

Formula: C₁₂H₁₉ClN₄O₇P₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 460.7674

Ref: IN-DA00AK3K

Thiamine pyrophosphate

CAS: 154-87-0

Thiamine pyrophosphate

Purity: ≥98%

Molecular weight: 460.76g/mol

Ref: 54-BUP17496

Thiamine pyrophosphate

CAS: 154-87-0

Formula: C₁₂H₁₉ClN₄O₇P₂S

Purity: ≥ 95.0%

Color and Shape: White to off-white powder

Molecular weight: 460.77

Ref: 7W-GV8106

Thiamine Diphosphate

CAS: 154-87-0

Thiamine Diphosphate

Formula: C₁₂H₁₉N₄O₇P₂S·Cl

Purity: 98%

Color and Shape: white to off-white powder

Molecular weight: 460.77g/mol

Ref: 54-OR1015232

Thiamine pyrophosphate chloride

CAS: 154-87-0

Formula: C₁₂H₁₉N₄O₇P₂S·Cl

Color and Shape: Off-White

Molecular weight: 460.77

Ref: 04-C17455700

Thiamine pyrophosphate chloride

CAS: 154-87-0

Thiamine pyrophosphate, a vitamin B1 derivative, is a coenzyme in transketolase studies for decarboxylation in biology.

Formula: C₁₂H₁₉ClN₄O₇P₂S

Purity: 98.29% - 99.72%

Color and Shape: Solid

Molecular weight: 460.76

Ref: TM-T4874

Thiamine Pyrophosphate

CAS: 154-87-0

Formula: C₁₂H₁₉N₄O₇P₂S·Cl

Molecular weight: 425.31 35.45

Ref: 4Z-T-8436

Thiamine Pyrophosphate Chloride

CAS: 154-87-0

Stability Hygroscopic
Applications Thiamine Pyrophosphate is a thiamine (T344185) derivative produced by enzyme thiamine pyrophosphatase. Thiamine pyrophosphate is a cofactor used to catalyze various biochemical reactions.
References Andrews, F.H. et al.: Biochem., 52, 3028 (2013); Mueller, C.R., et al.: Org. Biomolec. Chem., 11, 2000 (2013); Haag, N., et al.: J. Neurosci., 32, 17842 (2012); Nemeria, N., et al.: Biochem., 51, 7940 (2012);

Formula: C₁₂H₁₉N₄O₇P₂S·Cl

Color and Shape: Off-White

Molecular weight: 460.77

Ref: TR-T344070

Thiamine Pyrophosphate

CAS: 154-87-0

Applications Thiamine pyrophosphate (cas# 154-87-0) is a useful research chemical.

Formula: C₁₂H₁₉N₄O₇P₂S·Cl

Color and Shape: Neat

Molecular weight: 460.77

Ref: TR-T344268

Thiamine pyrophosphate

CAS: 154-87-0

Thiamine derivative; coenzyme of transketolase

Formula: C₁₂H₁₉ClN₄O₇P₂S

Purity: Min. 93%

Color and Shape: White Powder

Molecular weight: 460.77 g/mol

Ref: 3D-FT29444

Thiamine pyrophosphate

CAS: 154-87-0

Please enquire for more information about Thiamine pyrophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₂H₁₉ClN₄O₇P₂S

Purity: Min. 93%

Molecular weight: 460.77 g/mol

Ref: 3D-J-009154

Cocarboxylase

CAS: 154-87-0

Purity: 98%

Molecular weight: 460.7600098

Ref: 10-F797112