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CAS 154-97-2

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Pralidoxime mesylate

Description:
Pralidoxime mesylate, with the CAS number 154-97-2, is a chemical compound primarily used as an antidote for organophosphate poisoning, which affects the nervous system by inhibiting acetylcholinesterase. This compound acts by reactivating the inhibited enzyme, thereby restoring normal neurotransmission. Pralidoxime mesylate is a quaternary ammonium compound, which contributes to its solubility in water and its ability to penetrate biological membranes to some extent. It is typically administered via intravenous or intramuscular routes. The substance is characterized by its ability to form a stable complex with organophosphates, facilitating their removal from the enzyme. In addition to its therapeutic applications, pralidoxime mesylate is also studied for its potential in treating other conditions related to cholinergic dysfunction. Safety and efficacy are critical considerations in its use, and it is generally well-tolerated, although side effects may occur. Overall, pralidoxime mesylate plays a vital role in emergency medicine, particularly in cases of pesticide exposure or nerve agent poisoning.
Formula:C7H9N2O·CH3O3S
InChI:InChI=1S/C7H8N2O.CH4O3S/c1-9-5-3-2-4-7(9)6-8-10;1-5(2,3)4/h2-6H,1H3;1H3,(H,2,3,4)
InChI key:InChIKey=WWZYJJGFUIAWNW-UHFFFAOYSA-N
SMILES:S(C)(=O)(=O)[O-].C(=NO)C=1[N+](C)=CC=CC1
Synonyms:
  • (E)-(1-methylpyridin-2(1H)-ylidene)-N-oxomethanaminium methanesulfonate
  • 1-Methyl-2-(hydroxyiminomethyl)pyridinium methanesulfonate
  • 1-Methylpyridinium-2-aldoxime methanesulfonate
  • 2-(Hydroxyiminomethyl)-1-methylpyridinium methanesulfonate
  • 2-(Hydroxyiminomethyl)-N-methylpyridinium methanesulfonate
  • 2-Formyl-1-methylpyridinium methanesulfonate, oxime
  • 2-PAM methanesulfonate
  • 2-Pyridinealdoxime methyl methanesulfonate
  • 2-[(Z)-(hydroxyimino)methyl]-1-methylpyridinium methanesulfonate
  • Contrathion
  • See more synonyms
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