CAS 154026-93-4

Hexanoic acid, 6-chloro-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S)-

Description:

Hexanoic acid, 6-chloro-3,5-dihydroxy-, 1,1-dimethylethyl ester, with the CAS number 154026-93-4, is an organic compound characterized by its ester functional group derived from hexanoic acid. This compound features a chloro substituent at the sixth carbon and two hydroxyl groups at the third and fifth positions, contributing to its potential reactivity and solubility properties. The presence of the tert-butyl group (1,1-dimethylethyl) enhances its hydrophobic characteristics while providing steric hindrance, which can influence its biological activity and interactions. The specific stereochemistry, indicated by the (3R,5S) configuration, suggests that the compound may exhibit chiral properties, affecting its behavior in biological systems and its interactions with enzymes or receptors. Overall, this compound may have applications in pharmaceuticals or agrochemicals, where its unique structural features could impart specific functionalities or enhance efficacy.

Formula: C₁₀H₁₉ClO₄

InChI: InChI=1/C10H19ClO4/c1-10(2,3)15-9(14)5-7(12)4-8(13)6-11/h7-8,12-13H,4-6H2,1-3H3/t7-,8+/m1/s1

Synonyms:

• tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate

Hexanoic acid, 6-chloro-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S)-

CAS: 154026-93-4

Formula: C₁₀H₁₉ClO₄

Color and Shape: Liquid

Molecular weight: 238.7085

Ref: IN-DA007XTZ

Rosuvastatin Impurity 27

CAS: 154026-93-4

Formula: C₁₀H₁₉ClO₄

Molecular weight: 238.71

Ref: 4Z-R-0983

Rosuvastatin Impurity 125

CAS: 154026-93-4

Formula: C₁₀H₁₉ClO₄

Molecular weight: 238.71

Ref: 4Z-R-0949

(3R,5S)-tert-Butyl 6-chloro-3,5-dihydroxyhexanoate

CAS: 154026-93-4

(3R,5S)-tert-Butyl 6-chloro-3,5-dihydroxyhexanoate is a secondary metabolite that is used as a lipid-lowering drug. It is synthesized by an asymmetric synthesis of 3,5-dihydroxyhexanoic acid and tertiary butyl alcohol. The synthetic pathway starts with the conversion of diaminopentane phosphate to diaminopentane dihydrogen phosphate in the presence of sodium carbonate. This reaction produces a mixture of (2S,4S)- and (2R,4S) -enantiomers of diaminopentane dihydrogen phosphate. The (2S,4S) -enantiomer is then converted to (2R,4S) -enantiomer by dehydrogenase enzymes. Hydroxylation of the (2R,4S) -enantiomer occurs with the help of a lipase enzyme

Formula: C₁₀H₁₉ClO₄

Purity: Min. 95%

Molecular weight: 238.71 g/mol

Ref: 3D-EGA02693

Rosuvastatin Impurity 72

CAS: 154026-93-4

Formula: C₁₀H₁₉ClO₄

Molecular weight: 238.71

Ref: ST-EA-CP-R1132

1,1-Dimethylethyl (3R,5S)-6-Chloro-3,5-dihydroxyhexanoate

Controlled Product

CAS: 154026-93-4

Stability Hygroscopic
Applications (3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester is an intermediate in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor.
References Amidjojo, M., et al.: App. Microbiol. Biotechol., 69, 9 (2005);

Formula: C₁₀H₁₉ClO₄

Purity: ~90%

Color and Shape: Neat

Molecular weight: 238.71

Ref: TR-C365815