CAS 154032-37-8

Hydrocortisone EP Impurity O (19-Hydroxy Hydrocortisone)

CAS: 154032-37-8

Formula: C₂₁H₃₀O₆

Molecular weight: 378.47

Ref: 4Z-H-103015

19-Hydroxycortisol

CAS: 154032-37-8

Impurity Hydrocortisone EP Impurity O
Applications 19-Hydroxycortisol (Hydrocortisone EP Impurity O) is a derivative of Cortisol (H714615), a glucocorticoid produced by the zona fasciculata of the adrenal gland.
References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),

Formula: C₂₁H₃₀O₆

Color and Shape: Neat

Molecular weight: 378.459

Ref: TR-H918440

19-Hydroxycortisol

Controlled Product

CAS: 154032-37-8

19-Hydroxycortisol is a metabolite of cortisol, the main hormone released by the adrenal cortex. Cortisol is synthesized from cholesterol, and its production is stimulated by ACTH. 19-Hydroxycortisol can be transformed into cortisone in the presence of 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). The transformation of 19-hydroxycortisol to cortisone is an important step in the synthesis of cortisol.19-Hydroxycortisol has a chemical transformation that prevents it from being used as a mineralocorticoid receptor agonist, which would cause hypertension and fluid retention.

Formula: C₂₁H₃₀O₆

Purity: Min. 95%

Molecular weight: 378.5 g/mol

Ref: 3D-EGA03237

Hydrocortisone EP Impurity O

CAS: 154032-37-8

Formula: C₂₁H₃₀O₆

Molecular weight: 378.47

Ref: ST-EA-CP-H9015