CAS 154110-40-4

5'-o-(4,4'-Dimethoxytrityl)-N4-acetyl-2deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

Description:

5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite is a synthetic nucleoside derivative commonly used in the field of oligonucleotide synthesis. This compound features a modified cytidine base, which includes an acetyl group at the N4 position and a 5'-dimethoxytrityl protecting group, enhancing its stability and solubility during synthesis. The phosphoramidite functionality at the 3' position allows for efficient coupling in automated DNA synthesis, facilitating the formation of phosphodiester bonds. The presence of the cyanoethyl and diisopropyl groups contributes to the overall reactivity and solubility of the molecule, making it suitable for incorporation into oligonucleotides. This compound is typically utilized in research and therapeutic applications, particularly in the development of antisense oligonucleotides and RNA interference technologies. Its structural modifications are designed to improve the pharmacokinetic properties of the resulting nucleic acids, enhancing their efficacy and stability in biological systems.

Formula: C₄₁H₅₀N₅O₈P

Synonyms:

• Ac-dC Phosphoramidite
• (2R,3S,5R)-5-(4-Acetamido-2-Oxopyrimidin-1(2H)-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)Tetrahydrofuran-3-Yl 2-Cyanoethyl Diisopropylphosphoramidite
• N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite

Ac-dC Phosphoramidite

CAS: 154110-40-4

Formula: C₄₁H₅₀N₅O₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 771.8382

Ref: IN-DA007XRT

DMT-dC(ac) Phosphorous Amide

CAS: 154110-40-4

DMT-dC(ac) Phosphorous Amide

Purity: 95%

Molecular weight: 771.84g/mol

Ref: 54-OR1013055

DMT-dC(ac) Phosphoramidite

CAS: 154110-40-4

DMT-dC(ac) Phosphoramidite is a phosphoramidite monomer that has been modified for use in oligonucleotide synthesis.

Formula: C₄₁H₅₀N₅O₈P

Color and Shape: Solid

Molecular weight: 771.84

Ref: TM-T36753

N4-Acetyl-2''-deoxy-5''-O-DMT-cytidine 3''-CE phosphoramidite

CAS: 154110-40-4

Formula: C₄₁H₅₀N₅O₈P

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 771.84

Ref: 7W-GN5260

N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite

CAS: 154110-40-4

N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside that belongs to the group of deoxyribonucleosides. It is a modified nucleotide with a phosphate at the 5' position and an acetyl group in place of the hydroxyl group at the 2' position. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite has antiviral, anticancer, and activator properties. This compound is also known as 5′N4 acetyldeoxythymidine 3′Ce, or 5′N4 acetyldeoxythymidine 3′Ce phosphoramidite.

Formula: C₄₁H₅₀N₅O₈P

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 771.86 g/mol

Ref: 3D-PA09393

DMT-dC(ac) Phosphoramidite

CAS: 154110-40-4

Purity: 98%

Color and Shape: Solid

Molecular weight: 771.852

Ref: 10-F987458

DMT-dC(ac) Phosphoramidite

CAS: 154110-40-4

Formula: C₄₁H₅₀N₅O₈P

Molecular weight: 771.84

Ref: ST-EA-CP-C151020