
CAS 1541171-67-8
:(S)-N-((S)-1-(((2S,4S)-1-Chloro-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
Description:
The chemical substance with the name "(S)-N-((S)-1-(((2S,4S)-1-Chloro-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide" and CAS number "1541171-67-8" is a complex organic compound characterized by its chiral centers and multiple functional groups. It features amide linkages, a chloro group, and various alkyl and aryl substituents, contributing to its potential biological activity. The presence of morpholino and phenyl groups suggests possible interactions with biological targets, making it of interest in medicinal chemistry. Its stereochemistry, indicated by the (S) configurations, is crucial for its pharmacological properties, as chirality can significantly influence the compound's efficacy and safety profile. This compound may be investigated for its therapeutic applications, particularly in areas related to peptide mimetics or enzyme inhibitors, although specific biological activities would require empirical studies to elucidate its mechanism of action and potential uses.
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Found 4 products.
(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S,3S)-4-chloro-3-hydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-L-phenylalaninamide
CAS:Formula:C40H58ClN5O7Purity:95%Molecular weight:756.3708Carfilzomib Impurity 15
CAS:Formula:C40H58ClN5O7Color and Shape:Off-White SolidMolecular weight:756.38(alphaS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S,3S)-4-chloro-3-hydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-L-phenylalaninamide
CAS:Controlled Product<p>Applications (αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S,3S)-4-chloro-3-hydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-L-phenylalaninamide is an impurtiy of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C40H58ClN5O7Color and Shape:Off-WhiteMolecular weight:756.371



