Tubulin inhibitor 43, identified by its CAS number 1541208-02-9, is a synthetic compound that functions primarily as an inhibitor of tubulin polymerization. This characteristic makes it a valuable tool in cancer research, as it can disrupt the normal mitotic process by preventing the formation of microtubules, which are essential for cell division. The compound typically exhibits a specific binding affinity for the tubulin protein, leading to alterations in cellular dynamics and potentially inducing apoptosis in rapidly dividing cancer cells. Its chemical structure often includes functional groups that enhance its solubility and bioavailability, which are critical for its efficacy in biological systems. Additionally, studies may explore its pharmacokinetics, toxicity profiles, and potential therapeutic applications, particularly in the context of various malignancies. As with many tubulin inhibitors, understanding the mechanism of action and resistance patterns is crucial for optimizing its use in clinical settings.

Tubulin inhibitor 43

1541208-02-9: Tubulin inhibitor 43, identified by its CAS number 1541208-02-9, is a synthetic compound that functions primarily as an inhibitor of tubulin polymerization. This characteristic makes it a valuable tool in cancer research, as it can disrupt the normal mitotic process by preventing the formation of microtubules, which are essential for cell division. The compound typically exhibits a specific binding affinity for the tubulin protein, leading to alterations in cellular dynamics and potentially inducing apoptosis in rapidly dividing cancer cells. Its chemical structure often includes functional groups that enhance its solubility and bioavailability, which are critical for its efficacy in biological systems. Additionally, studies may explore its pharmacokinetics, toxicity profiles, and potential therapeutic applications, particularly in the context of various malignancies. As with many tubulin inhibitors, understanding the mechanism of action and resistance patterns is crucial for optimizing its use in clinical settings.

<p>Tubulin inhibitor 43 exhibits significant antitumor activity by impeding the proliferation and growth of cancer cells through the inhibition of β-microtubulin activity, ultimately inducing apoptosis [1].</p>

CAS 1541208-02-9

Tubulin inhibitor 43

Tubulin inhibitor 43

Ref: TM-T87575