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CAS 154127-19-2

:

Brinzolamide

Description:
Brinzolamide is a carbonic anhydrase inhibitor primarily used in the treatment of elevated intraocular pressure in conditions such as glaucoma and ocular hypertension. It is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. The chemical formula of brinzolamide reflects its complex structure, which includes a sulfonamide group, contributing to its pharmacological activity. As a topical ophthalmic agent, it works by reducing the production of aqueous humor in the eye, thereby lowering intraocular pressure. Brinzolamide is typically administered as an eye drop formulation, and its efficacy is enhanced when used in combination with other medications. The substance is generally well-tolerated, although some patients may experience local ocular side effects such as burning or stinging upon application. Its mechanism of action and therapeutic use make it a valuable option in managing conditions associated with increased intraocular pressure.
Formula:C12H21N3O5S3
InChI:InChI=1/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1
SMILES:CCN[C@H]1CN(CCCOC)S(=O)(=O)c2c1cc(s2)S(=O)(=O)N
Synonyms:
  • Birnzolamide
  • 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-
  • 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (R)-
  • Al 4862
  • Brinlolamide
  • (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
  • (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide
  • (4R)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
  • 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide
  • 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (S)-
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