Azicemicin A is a natural product belonging to the class of macrolide antibiotics, characterized by its complex structure that includes a large lactone ring. It is derived from the fermentation of specific bacterial strains, particularly those in the genus Micromonospora. Azicemicin A exhibits potent antibacterial activity, particularly against Gram-positive bacteria, making it a subject of interest in pharmaceutical research. Its mechanism of action typically involves inhibition of protein synthesis, which is a common feature among macrolide antibiotics. The compound is known for its unique stereochemistry and functional groups, which contribute to its biological activity and stability. Additionally, azicemicin A has been studied for its potential applications in treating various infections, although its clinical use may be limited by factors such as resistance and toxicity. Overall, azicemicin A represents a significant example of the diverse chemical structures found in natural antibiotics and highlights the ongoing exploration of microbial metabolites in drug discovery.

azicemicin A

154163-93-6: Azicemicin A is a natural product belonging to the class of macrolide antibiotics, characterized by its complex structure that includes a large lactone ring. It is derived from the fermentation of specific bacterial strains, particularly those in the genus Micromonospora. Azicemicin A exhibits potent antibacterial activity, particularly against Gram-positive bacteria, making it a subject of interest in pharmaceutical research. Its mechanism of action typically involves inhibition of protein synthesis, which is a common feature among macrolide antibiotics. The compound is known for its unique stereochemistry and functional groups, which contribute to its biological activity and stability. Additionally, azicemicin A has been studied for its potential applications in treating various infections, although its clinical use may be limited by factors such as resistance and toxicity. Overall, azicemicin A represents a significant example of the diverse chemical structures found in natural antibiotics and highlights the ongoing exploration of microbial metabolites in drug discovery.

<p>Azicemicin A exhibits mild antibacterial activity and shows no acute toxicity when administered via intraperitoneal injection to mice at a dosage of 150 mg/kg.</p>

CAS 154163-93-6

azicemicin A

Azicemicin A

Ref: TM-TN10694